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Phase I/II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with advanced malignancies.
Karapanagiotou EM, Roulstone V, Twigger K, Ball M, Tanay M, Nutting C, Newbold K, Gore ME, Larkin J, Syrigos KN, Coffey M, Thompson B, Mettinger K, Vile RG, Pandha HS, Hall GD, Melcher AA, Chester J, Harrington KJ. Karapanagiotou EM, et al. Among authors: thompson b. Clin Cancer Res. 2012 Apr 1;18(7):2080-9. doi: 10.1158/1078-0432.CCR-11-2181. Epub 2012 Feb 7. Clin Cancer Res. 2012. PMID: 22316603 Free PMC article. Clinical Trial.
Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy.
Twigger K, Vidal L, White CL, De Bono JS, Bhide S, Coffey M, Thompson B, Vile RG, Heinemann L, Pandha HS, Errington F, Melcher AA, Harrington KJ. Twigger K, et al. Among authors: thompson b. Clin Cancer Res. 2008 Feb 1;14(3):912-23. doi: 10.1158/1078-0432.CCR-07-1400. Clin Cancer Res. 2008. PMID: 18245555
Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway.
Twigger K, Roulstone V, Kyula J, Karapanagiotou EM, Syrigos KN, Morgan R, White C, Bhide S, Nuovo G, Coffey M, Thompson B, Jebar A, Errington F, Melcher AA, Vile RG, Pandha HS, Harrington KJ. Twigger K, et al. Among authors: thompson b. BMC Cancer. 2012 Aug 24;12:368. doi: 10.1186/1471-2407-12-368. BMC Cancer. 2012. PMID: 22920673 Free PMC article.
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates.
Yang WQ, Lun X, Palmer CA, Wilcox ME, Muzik H, Shi ZQ, Dyck R, Coffey M, Thompson B, Hamilton M, Nishikawa SG, Brasher PM, Fonseca K, George D, Rewcastle NB, Johnston RN, Stewart D, Lee PW, Senger DL, Forsyth PA. Yang WQ, et al. Among authors: thompson b. Clin Cancer Res. 2004 Dec 15;10(24):8561-76. doi: 10.1158/1078-0432.CCR-04-0940. Clin Cancer Res. 2004. PMID: 15623640
A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas.
Forsyth P, Roldán G, George D, Wallace C, Palmer CA, Morris D, Cairncross G, Matthews MV, Markert J, Gillespie Y, Coffey M, Thompson B, Hamilton M. Forsyth P, et al. Among authors: thompson b. Mol Ther. 2008 Mar;16(3):627-32. doi: 10.1038/sj.mt.6300403. Epub 2008 Feb 5. Mol Ther. 2008. PMID: 18253152 Free article. Clinical Trial.
The oncolytic virus, pelareorep, as a novel anticancer agent: a review.
Chakrabarty R, Tran H, Selvaggi G, Hagerman A, Thompson B, Coffey M. Chakrabarty R, et al. Among authors: thompson b. Invest New Drugs. 2015 Jun;33(3):761-74. doi: 10.1007/s10637-015-0216-8. Epub 2015 Feb 19. Invest New Drugs. 2015. PMID: 25693885 Review.
A phase II study of REOLYSIN® (pelareorep) in combination with carboplatin and paclitaxel for patients with advanced malignant melanoma.
Mahalingam D, Fountzilas C, Moseley J, Noronha N, Tran H, Chakrabarty R, Selvaggi G, Coffey M, Thompson B, Sarantopoulos J. Mahalingam D, et al. Among authors: thompson b. Cancer Chemother Pharmacol. 2017 Apr;79(4):697-703. doi: 10.1007/s00280-017-3260-6. Epub 2017 Mar 13. Cancer Chemother Pharmacol. 2017. PMID: 28289863 Clinical Trial.
Evaluation of homogeneity and genetic stability of REOLYSIN (pelareorep) by complete genome sequencing of reovirus after large scale production.
Chakrabarty R, Tran H, Fortin Y, Yu Z, Shen SH, Kolman J, Onions D, Voyer R, Hagerman A, Serl S, Kamen A, Thompson B, Coffey M. Chakrabarty R, et al. Among authors: thompson b. Appl Microbiol Biotechnol. 2014 Feb;98(4):1763-70. doi: 10.1007/s00253-013-5499-0. Epub 2014 Jan 14. Appl Microbiol Biotechnol. 2014. PMID: 24419798
3,695 results