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Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells.
Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, Alfaro-Cervello C, Saini HK, Davis MP, Schaeffer J, Vega B, Stefanini M, Zhao C, Muller W, Garcia-Verdugo JM, Mathivanan S, Bachi A, Enright AJ, Mattick JS, Pluchino S. Cossetti C, et al. Mol Cell. 2014 Oct 23;56(2):193-204. doi: 10.1016/j.molcel.2014.08.020. Epub 2014 Sep 18. Mol Cell. 2014. PMID: 25242146 Free PMC article.
Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function.
Pluchino S, Zanotti L, Brambilla E, Rovere-Querini P, Capobianco A, Alfaro-Cervello C, Salani G, Cossetti C, Borsellino G, Battistini L, Ponzoni M, Doglioni C, Garcia-Verdugo JM, Comi G, Manfredi AA, Martino G. Pluchino S, et al. Among authors: cossetti c. PLoS One. 2009 Jun 19;4(6):e5959. doi: 10.1371/journal.pone.0005959. PLoS One. 2009. PMID: 19543526 Free PMC article.
The stem cell secretome and its role in brain repair.
Drago D, Cossetti C, Iraci N, Gaude E, Musco G, Bachi A, Pluchino S. Drago D, et al. Among authors: cossetti c. Biochimie. 2013 Dec;95(12):2271-85. doi: 10.1016/j.biochi.2013.06.020. Epub 2013 Jul 1. Biochimie. 2013. PMID: 23827856 Free PMC article. Review.
Extracellular vesicles are independent metabolic units with asparaginase activity.
Iraci N, Gaude E, Leonardi T, Costa ASH, Cossetti C, Peruzzotti-Jametti L, Bernstock JD, Saini HK, Gelati M, Vescovi AL, Bastos C, Faria N, Occhipinti LG, Enright AJ, Frezza C, Pluchino S. Iraci N, et al. Among authors: cossetti c. Nat Chem Biol. 2017 Sep;13(9):951-955. doi: 10.1038/nchembio.2422. Epub 2017 Jul 3. Nat Chem Biol. 2017. PMID: 28671681 Free PMC article.
39 results