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Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus.
Volpi SA, Verma-Gaur J, Hassan R, Ju Z, Roa S, Chatterjee S, Werling U, Hou H Jr, Will B, Steidl U, Scharff M, Edelman W, Feeney AJ, Birshtein BK. Volpi SA, et al. Among authors: birshtein bk. J Immunol. 2012 Mar 15;188(6):2556-66. doi: 10.4049/jimmunol.1102763. Epub 2012 Feb 17. J Immunol. 2012. PMID: 22345664 Free PMC article.
Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites.
Garrett FE, Emelyanov AV, Sepulveda MA, Flanagan P, Volpi S, Li F, Loukinov D, Eckhardt LA, Lobanenkov VV, Birshtein BK. Garrett FE, et al. Among authors: birshtein bk. Mol Cell Biol. 2005 Feb;25(4):1511-25. doi: 10.1128/MCB.25.4.1511-1525.2005. Mol Cell Biol. 2005. PMID: 15684400 Free PMC article.
Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.
Giambra V, Volpi S, Emelyanov AV, Pflugh D, Bothwell AL, Norio P, Fan Y, Ju Z, Skoultchi AI, Hardy RR, Frezza D, Birshtein BK. Giambra V, et al. Among authors: birshtein bk. Mol Cell Biol. 2008 Oct;28(19):6123-33. doi: 10.1128/MCB.00233-08. Epub 2008 Jul 21. Mol Cell Biol. 2008. PMID: 18644860 Free PMC article.
CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells.
Degner SC, Verma-Gaur J, Wong TP, Bossen C, Iverson GM, Torkamani A, Vettermann C, Lin YC, Ju Z, Schulz D, Murre CS, Birshtein BK, Schork NJ, Schlissel MS, Riblet R, Murre C, Feeney AJ. Degner SC, et al. Among authors: birshtein bk. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9566-71. doi: 10.1073/pnas.1019391108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606361 Free PMC article.
82 results