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Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus.
Volpi SA, Verma-Gaur J, Hassan R, Ju Z, Roa S, Chatterjee S, Werling U, Hou H Jr, Will B, Steidl U, Scharff M, Edelman W, Feeney AJ, Birshtein BK. Volpi SA, et al. Among authors: scharff m. J Immunol. 2012 Mar 15;188(6):2556-66. doi: 10.4049/jimmunol.1102763. Epub 2012 Feb 17. J Immunol. 2012. PMID: 22345664 Free PMC article.
Does antisense make sense of AID targeting?
Roa S, Kuang FL, Scharff MD. Roa S, et al. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3661-2. doi: 10.1073/pnas.0800935105. Epub 2008 Mar 5. Proc Natl Acad Sci U S A. 2008. PMID: 18322011 Free PMC article. No abstract available.
AIDing antibody diversity by error-prone mismatch repair.
Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Semin Immunol. 2012 Aug;24(4):293-300. doi: 10.1016/j.smim.2012.05.005. Epub 2012 Jun 14. Semin Immunol. 2012. PMID: 22703640 Free PMC article. Review.
The biochemistry of somatic hypermutation.
Peled JU, Kuang FL, Iglesias-Ussel MD, Roa S, Kalis SL, Goodman MF, Scharff MD. Peled JU, et al. Annu Rev Immunol. 2008;26:481-511. doi: 10.1146/annurev.immunol.26.021607.090236. Annu Rev Immunol. 2008. PMID: 18304001 Review.
271 results