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Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.
Van de Putte T, Maruhashi M, Francis A, Nelles L, Kondoh H, Huylebroeck D, Higashi Y. Van de Putte T, et al. Among authors: francis a. Am J Hum Genet. 2003 Feb;72(2):465-70. doi: 10.1086/346092. Epub 2003 Jan 9. Am J Hum Genet. 2003. PMID: 12522767 Free PMC article.
Slowed conduction and thin myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10.
Verhoeven K, De Jonghe P, Van de Putte T, Nelis E, Zwijsen A, Verpoorten N, De Vriendt E, Jacobs A, Van Gerwen V, Francis A, Ceuterick C, Huylebroeck D, Timmerman V. Verhoeven K, et al. Among authors: francis a. Am J Hum Genet. 2003 Oct;73(4):926-32. doi: 10.1086/378159. Epub 2003 Aug 19. Am J Hum Genet. 2003. PMID: 14508709 Free PMC article.
Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo.
Conidi A, Cazzola S, Beets K, Coddens K, Collart C, Cornelis F, Cox L, Joke D, Dobreva MP, Dries R, Esguerra C, Francis A, Ibrahimi A, Kroes R, Lesage F, Maas E, Moya I, Pereira PN, Stappers E, Stryjewska A, van den Berghe V, Vermeire L, Verstappen G, Seuntjens E, Umans L, Zwijsen A, Huylebroeck D. Conidi A, et al. Among authors: francis a. Cytokine Growth Factor Rev. 2011 Oct-Dec;22(5-6):287-300. doi: 10.1016/j.cytogfr.2011.11.006. Epub 2011 Nov 26. Cytokine Growth Factor Rev. 2011. PMID: 22119658 Review.
Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.
van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E. van den Berghe V, et al. Among authors: francis a. Neuron. 2013 Jan 9;77(1):70-82. doi: 10.1016/j.neuron.2012.11.009. Neuron. 2013. PMID: 23312517 Free article.
1,152 results