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Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency.
Herreman A, Hartmann D, Annaert W, Saftig P, Craessaerts K, Serneels L, Umans L, Schrijvers V, Checler F, Vanderstichele H, Baekelandt V, Dressel R, Cupers P, Huylebroeck D, Zwijsen A, Van Leuven F, De Strooper B. Herreman A, et al. Among authors: zwijsen a. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11872-7. doi: 10.1073/pnas.96.21.11872. Proc Natl Acad Sci U S A. 1999. PMID: 10518543 Free PMC article.
Smad5 is essential for left-right asymmetry in mice.
Chang H, Zwijsen A, Vogel H, Huylebroeck D, Matzuk MM. Chang H, et al. Among authors: zwijsen a. Dev Biol. 2000 Mar 1;219(1):71-8. doi: 10.1006/dbio.1999.9594. Dev Biol. 2000. PMID: 10677256 Free article.
89 results