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Page 1
Evolutionary genetics of the human Rh blood group system.
Perry GH, Xue Y, Smith RS, Meyer WK, Calışkan M, Yanez-Cuna O, Lee AS, Gutiérrez-Arcelus M, Ober C, Hollox EJ, Tyler-Smith C, Lee C. Perry GH, et al. Hum Genet. 2012 Jul;131(7):1205-16. doi: 10.1007/s00439-012-1147-5. Epub 2012 Feb 25. Hum Genet. 2012. PMID: 22367406 Free PMC article.
IFN- γ and TNF- α drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation.
Zhang F, Mears JR, Shakib L, Beynor JI, Shanaj S, Korsunsky I, Nathan A; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium; Donlin LT, Raychaudhuri S. Zhang F, et al. bioRxiv [Preprint]. 2020 Aug 5:2020.08.05.238360. doi: 10.1101/2020.08.05.238360. bioRxiv. 2020. Update in: Genome Med. 2021 Apr 20;13(1):64. doi: 10.1186/s13073-021-00881-3 PMID: 32793902 Free PMC article. Updated. Preprint.
Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps.
Huang GX, Hallen NR, Lee M, Zheng K, Wang X, Mandanas MV, Djeddi S, Fernandez D, Hacker J, Ryan T, Bergmark RW, Bhattacharyya N, Lee S, Maxfield AZ, Roditi RE, Buchheit KM, Laidlaw TM, Gern JE, Hallstrand TS, Ray A, Wenzel SE, Boyce JA, Gutierrez-Arcelus M, Barrett NA. Huang GX, et al. bioRxiv [Preprint]. 2023 Oct 17:2023.10.13.562288. doi: 10.1101/2023.10.13.562288. bioRxiv. 2023. PMID: 37904989 Free PMC article. Preprint.
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM 2nd, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF; Accelerating Medicines Partnership: RA/SLE Network; Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Zhang F, et al. Nature. 2023 Nov;623(7987):616-624. doi: 10.1038/s41586-023-06708-y. Epub 2023 Nov 8. Nature. 2023. PMID: 37938773 Free PMC article.
Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis.
Chiñas M, Fernandez-Salinas D, Aguiar VRC, Nieto-Caballero VE, Lefton M, Nigrovic PA, Ermann J, Gutierrez-Arcelus M. Chiñas M, et al. medRxiv [Preprint]. 2024 May 9:2023.09.21.23295912. doi: 10.1101/2023.09.21.23295912. medRxiv. 2024. Update in: HGG Adv. 2024 Oct 28;6(1):100375. doi: 10.1016/j.xhgg.2024.100375 PMID: 37808698 Free PMC article. Updated. Preprint.
Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant.
Wang Q, Martínez-Bonet M, Kim T, Sparks JA, Ishigaki K, Chen X, Sudman M, Aguiar V, Sim S, Hernandez MC, Chiu DJ, Wactor A, Wauford B, Marion MC, Gutierrez-Arcelus M, Bowes J, Eyre S, Nordal E, Prahalad S, Rygg M, Videm V, Raychaudhuri S, Weirauch MT, Langefeld CD, Thompson SD, Nigrovic PA. Wang Q, et al. Cell Genom. 2023 Oct 16;3(11):100420. doi: 10.1016/j.xgen.2023.100420. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020975 Free PMC article.
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis.
Weinand K, Sakaue S, Nathan A, Jonsson AH, Zhang F, Watts GFM, Al Suqri M, Zhu Z; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Rao DA, Anolik JH, Brenner MB, Donlin LT, Wei K, Raychaudhuri S. Weinand K, et al. Nat Commun. 2024 May 31;15(1):4650. doi: 10.1038/s41467-024-48620-7. Nat Commun. 2024. PMID: 38821936 Free PMC article.
High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus.
Nigrovic PA, Wang Q, Kim T, Martinez-Bonet M, Aguiar VRC, Sim S, Cui J, Sparks JA, Chen X, Todd M, Wauford B, Marion MC, Langefeld CD, Weirauch MT, Gutierrez-Arcelus M. Nigrovic PA, et al. bioRxiv [Preprint]. 2024 Apr 12:2023.08.16.553538. doi: 10.1101/2023.08.16.553538. bioRxiv. 2024. Update in: Nat Commun. 2024 Aug 9;15(1):6804. doi: 10.1038/s41467-024-50710-5 PMID: 37645953 Free PMC article. Updated. Preprint.
70 results