Smith RP - Search Results

1

Massively parallel functional dissection of mammalian enhancers in vivo.

Patwardhan RP, Hiatt JB, Witten DM, Kim MJ, Smith RP, May D, Lee C, Andrie JM, Lee SI, Cooper GM, Ahituv N, Pennacchio LA, Shendure J. Patwardhan RP, et al. Among authors: smith rp. Nat Biotechnol. 2012 Feb 26;30(3):265-70. doi: 10.1038/nbt.2136. Nat Biotechnol. 2012. PMID: 22371081 Free PMC article.

2

Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model.

Smith RP, Taher L, Patwardhan RP, Kim MJ, Inoue F, Shendure J, Ovcharenko I, Ahituv N. Smith RP, et al. Nat Genet. 2013 Sep;45(9):1021-1028. doi: 10.1038/ng.2713. Epub 2013 Jul 28. Nat Genet. 2013. PMID: 23892608 Free PMC article.

3

Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation.

Birnbaum RY, Patwardhan RP, Kim MJ, Findlay GM, Martin B, Zhao J, Bell RJ, Smith RP, Ku AA, Shendure J, Ahituv N. Birnbaum RY, et al. Among authors: smith rp. PLoS Genet. 2014 Oct 23;10(10):e1004592. doi: 10.1371/journal.pgen.1004592. eCollection 2014 Oct. PLoS Genet. 2014. PMID: 25340400 Free PMC article.

4

Sequence signatures extracted from proximal promoters can be used to predict distal enhancers.

Taher L, Smith RP, Kim MJ, Ahituv N, Ovcharenko I. Taher L, et al. Among authors: smith rp. Genome Biol. 2013;14(10):R117. doi: 10.1186/gb-2013-14-10-r117. Genome Biol. 2013. PMID: 24156763 Free PMC article.

5

In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus.

Eclov RJ, Kim MJ, Smith RP, Liang X, Ahituv N, Kroetz DL. Eclov RJ, et al. Among authors: smith rp. Drug Metab Dispos. 2017 Feb;45(2):208-215. doi: 10.1124/dmd.116.072033. Epub 2016 Nov 17. Drug Metab Dispos. 2017. PMID: 27856528 Free PMC article.

6

Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity.

Eclov RJ, Kim MJ, Smith R, Ahituv N, Kroetz DL. Eclov RJ, et al. Drug Metab Dispos. 2018 May;46(5):636-642. doi: 10.1124/dmd.117.079541. Epub 2018 Feb 21. Drug Metab Dispos. 2018. PMID: 29467213 Free PMC article.

7

ABCG2 regulatory single-nucleotide polymorphisms alter in vivo enhancer activity and expression.

Eclov RJ, Kim MJ, Chhibber A, Smith RP, Ahituv N, Kroetz DL. Eclov RJ, et al. Among authors: smith rp. Pharmacogenet Genomics. 2017 Dec;27(12):454-463. doi: 10.1097/FPC.0000000000000312. Pharmacogenet Genomics. 2017. PMID: 28930109 Free PMC article.

8

Genome-wide identification of signaling center enhancers in the developing limb.

VanderMeer JE, Smith RP, Jones SL, Ahituv N. VanderMeer JE, et al. Among authors: smith rp. Development. 2014 Nov;141(21):4194-8. doi: 10.1242/dev.110965. Epub 2014 Oct 1. Development. 2014. PMID: 25273087 Free PMC article.

9

Pharmacogene regulatory elements: from discovery to applications.

Smith RP, Lam ET, Markova S, Yee SW, Ahituv N. Smith RP, et al. Genome Med. 2012 May 25;4(5):45. doi: 10.1186/gm344. Genome Med. 2012. PMID: 22630332 Free PMC article.

10

Genome-wide discovery of drug-dependent human liver regulatory elements.

Smith RP, Eckalbar WL, Morrissey KM, Luizon MR, Hoffmann TJ, Sun X, Jones SL, Force Aldred S, Ramamoorthy A, Desta Z, Liu Y, Skaar TC, Trinklein ND, Giacomini KM, Ahituv N. Smith RP, et al. PLoS Genet. 2014 Oct 2;10(10):e1004648. doi: 10.1371/journal.pgen.1004648. eCollection 2014 Oct. PLoS Genet. 2014. PMID: 25275310 Free PMC article.

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