Crooke RM - Search Results

1

Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice.

Carr RM, Patel RT, Rao V, Dhir R, Graham MJ, Crooke RM, Ahima RS. Carr RM, et al. Among authors: crooke rm. Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R996-1003. doi: 10.1152/ajpregu.00177.2011. Epub 2012 Feb 29. Am J Physiol Regul Integr Comp Physiol. 2012. PMID: 22378776 Free PMC article.

2

Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide.

Imai Y, Varela GM, Jackson MB, Graham MJ, Crooke RM, Ahima RS. Imai Y, et al. Among authors: crooke rm. Gastroenterology. 2007 May;132(5):1947-54. doi: 10.1053/j.gastro.2007.02.046. Epub 2007 Feb 23. Gastroenterology. 2007. PMID: 17484887

3

Adipose differentiation-related protein regulates lipids and insulin in pancreatic islets.

Faleck DM, Ali K, Roat R, Graham MJ, Crooke RM, Battisti R, Garcia E, Ahima RS, Imai Y. Faleck DM, et al. Among authors: crooke rm. Am J Physiol Endocrinol Metab. 2010 Aug;299(2):E249-57. doi: 10.1152/ajpendo.00646.2009. Epub 2010 May 18. Am J Physiol Endocrinol Metab. 2010. PMID: 20484013 Free PMC article.

4

Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice.

Liu Y, Millar JS, Cromley DA, Graham M, Crooke R, Billheimer JT, Rader DJ. Liu Y, et al. Biochim Biophys Acta. 2008 Mar;1781(3):97-104. doi: 10.1016/j.bbalip.2008.01.001. Epub 2008 Jan 17. Biochim Biophys Acta. 2008. PMID: 18252207

5

Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes.

Digenio A, Dunbar RL, Alexander VJ, Hompesch M, Morrow L, Lee RG, Graham MJ, Hughes SG, Yu R, Singleton W, Baker BF, Bhanot S, Crooke RM. Digenio A, et al. Among authors: crooke rm. Diabetes Care. 2016 Aug;39(8):1408-15. doi: 10.2337/dc16-0126. Epub 2016 Jun 6. Diabetes Care. 2016. PMID: 27271183 Clinical Trial.

6

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance.

Brown JM, Betters JL, Lord C, Ma Y, Han X, Yang K, Alger HM, Melchior J, Sawyer J, Shah R, Wilson MD, Liu X, Graham MJ, Lee R, Crooke R, Shulman GI, Xue B, Shi H, Yu L. Brown JM, et al. J Lipid Res. 2010 Nov;51(11):3306-15. doi: 10.1194/jlr.M010256. Epub 2010 Aug 27. J Lipid Res. 2010. PMID: 20802159 Free PMC article.

7

An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis.

Crooke RM, Graham MJ, Lemonidis KM, Whipple CP, Koo S, Perera RJ. Crooke RM, et al. J Lipid Res. 2005 May;46(5):872-84. doi: 10.1194/jlr.M400492-JLR200. Epub 2005 Feb 16. J Lipid Res. 2005. PMID: 15716585 Free article.

8

Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type diet.

Li G, Hernandez-Ono A, Crooke RM, Graham MJ, Ginsberg HN. Li G, et al. Among authors: crooke rm. Metabolism. 2012 Jun;61(6):823-35. doi: 10.1016/j.metabol.2011.11.008. Epub 2011 Dec 29. Metabolism. 2012. PMID: 22209663 Free PMC article.

9

The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis.

Ferguson D, Zhang J, Davis MA, Helsley RN, Vedin LL, Lee RG, Crooke RM, Graham MJ, Allende DS, Parini P, Brown JM. Ferguson D, et al. Among authors: crooke rm. J Lipid Res. 2017 Feb;58(2):420-432. doi: 10.1194/jlr.M073734. Epub 2016 Dec 10. J Lipid Res. 2017. PMID: 27941027 Free PMC article.

10

Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis.

Zhang YL, Hernandez-Ono A, Siri P, Weisberg S, Conlon D, Graham MJ, Crooke RM, Huang LS, Ginsberg HN. Zhang YL, et al. Among authors: crooke rm. J Biol Chem. 2006 Dec 8;281(49):37603-15. doi: 10.1074/jbc.M604709200. Epub 2006 Sep 12. J Biol Chem. 2006. PMID: 16971390 Free article.

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