Bender MA - Search Results

1

The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation.

Bender MA, Ragoczy T, Lee J, Byron R, Telling A, Dean A, Groudine M. Bender MA, et al. Blood. 2012 Apr 19;119(16):3820-7. doi: 10.1182/blood-2011-09-380485. Epub 2012 Feb 29. Blood. 2012. PMID: 22378846 Free PMC article.

2

Description and targeted deletion of 5' hypersensitive site 5 and 6 of the mouse beta-globin locus control region.

Bender MA, Reik A, Close J, Telling A, Epner E, Fiering S, Hardison R, Groudine M. Bender MA, et al. Blood. 1998 Dec 1;92(11):4394-403. Blood. 1998. PMID: 9834246 Free article.

3

Independent formation of DnaseI hypersensitive sites in the murine beta-globin locus control region.

Bender MA, Mehaffey MG, Telling A, Hug B, Ley TJ, Groudine M, Fiering S. Bender MA, et al. Blood. 2000 Jun 1;95(11):3600-4. Blood. 2000. PMID: 10828050 Free article.

4

The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes.

Schübeler D, Groudine M, Bender MA. Schübeler D, et al. Among authors: bender ma. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11432-7. doi: 10.1073/pnas.201394698. Epub 2001 Sep 11. Proc Natl Acad Sci U S A. 2001. PMID: 11553791 Free PMC article.

5

Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites.

Bender MA, Roach JN, Halow J, Close J, Alami R, Bouhassira EE, Groudine M, Fiering SN. Bender MA, et al. Blood. 2001 Oct 1;98(7):2022-7. doi: 10.1182/blood.v98.7.2022. Blood. 2001. PMID: 11567985 Free article.

6

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

Sawado T, Halow J, Bender MA, Groudine M. Sawado T, et al. Among authors: bender ma. Genes Dev. 2003 Apr 15;17(8):1009-18. doi: 10.1101/gad.1072303. Epub 2003 Apr 2. Genes Dev. 2003. PMID: 12672691 Free PMC article.

7

Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenes.

Hu X, Bulger M, Bender MA, Fields J, Groudine M, Fiering S. Hu X, et al. Among authors: bender ma. Blood. 2006 Jan 15;107(2):821-6. doi: 10.1182/blood-2005-06-2308. Epub 2005 Sep 27. Blood. 2006. PMID: 16189270 Free PMC article.

8

Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription.

Bender MA, Byron R, Ragoczy T, Telling A, Bulger M, Groudine M. Bender MA, et al. Blood. 2006 Aug 15;108(4):1395-401. doi: 10.1182/blood-2006-04-014431. Epub 2006 Apr 27. Blood. 2006. PMID: 16645164 Free PMC article.

9

The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation.

Ragoczy T, Bender MA, Telling A, Byron R, Groudine M. Ragoczy T, et al. Among authors: bender ma. Genes Dev. 2006 Jun 1;20(11):1447-57. doi: 10.1101/gad.1419506. Epub 2006 May 16. Genes Dev. 2006. PMID: 16705039 Free PMC article.

10

H3 K79 dimethylation marks developmental activation of the beta-globin gene but is reduced upon LCR-mediated high-level transcription.

Sawado T, Halow J, Im H, Ragoczy T, Bresnick EH, Bender MA, Groudine M. Sawado T, et al. Among authors: bender ma. Blood. 2008 Jul 15;112(2):406-14. doi: 10.1182/blood-2007-12-128983. Epub 2008 Apr 25. Blood. 2008. PMID: 18441235 Free PMC article.

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