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KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.
Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M; International Consortium for Blood Pressure (ICBP); Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X. Louis-Dit-Picard H, et al. Among authors: pylypenko o. Nat Genet. 2012 Mar 11;44(4):456-60, S1-3. doi: 10.1038/ng.2218. Nat Genet. 2012. PMID: 22406640
Oxidation of F-actin controls the terminal steps of cytokinesis.
Frémont S, Hammich H, Bai J, Wioland H, Klinkert K, Rocancourt M, Kikuti C, Stroebel D, Romet-Lemonne G, Pylypenko O, Houdusse A, Echard A. Frémont S, et al. Among authors: pylypenko o. Nat Commun. 2017 Feb 23;8:14528. doi: 10.1038/ncomms14528. Nat Commun. 2017. PMID: 28230050 Free PMC article.
The myosin X motor is optimized for movement on actin bundles.
Ropars V, Yang Z, Isabet T, Blanc F, Zhou K, Lin T, Liu X, Hissier P, Samazan F, Amigues B, Yang ED, Park H, Pylypenko O, Cecchini M, Sindelar CV, Sweeney HL, Houdusse A. Ropars V, et al. Among authors: pylypenko o. Nat Commun. 2016 Sep 1;7:12456. doi: 10.1038/ncomms12456. Nat Commun. 2016. PMID: 27580874 Free PMC article.
Force Generation by Myosin Motors: A Structural Perspective.
Robert-Paganin J, Pylypenko O, Kikuti C, Sweeney HL, Houdusse A. Robert-Paganin J, et al. Among authors: pylypenko o. Chem Rev. 2020 Jan 8;120(1):5-35. doi: 10.1021/acs.chemrev.9b00264. Epub 2019 Nov 5. Chem Rev. 2020. PMID: 31689091 Review.
Essential "ankle" in the myosin lever arm.
Pylypenko O, Houdusse AM. Pylypenko O, et al. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):5-6. doi: 10.1073/pnas.1017676108. Epub 2010 Dec 21. Proc Natl Acad Sci U S A. 2011. PMID: 21177429 Free PMC article. No abstract available.
44 results