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Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for enhanced survival of transplanted oligodendrocyte progenitors in X-irradiated compared to normal CNS.
Hinks GL, Chari DM, O'Leary MT, Zhao C, Keirstead HS, Blakemore WF, Franklin RJ. Hinks GL, et al. Among authors: franklin rj. Neuropathol Appl Neurobiol. 2001 Feb;27(1):59-67. doi: 10.1046/j.0305-1846.2001.00303.x. Neuropathol Appl Neurobiol. 2001. PMID: 11299003
Ageing and CNS remyelination.
Franklin RJ, Zhao C, Sim FJ. Franklin RJ, et al. Neuroreport. 2002 May 24;13(7):923-8. doi: 10.1097/00001756-200205240-00001. Neuroreport. 2002. PMID: 12004191 Review.
337 results