Powis G - Search Results

1

AMPKα modulation in cancer progression: multilayer integrative analysis of the whole transcriptome in Asian gastric cancer.

Kim YH, Liang H, Liu X, Lee JS, Cho JY, Cheong JH, Kim H, Li M, Downey TJ, Dyer MD, Sun Y, Sun J, Beasley EM, Chung HC, Noh SH, Weinstein JN, Liu CG, Powis G. Kim YH, et al. Among authors: powis g. Cancer Res. 2012 May 15;72(10):2512-21. doi: 10.1158/0008-5472.CAN-11-3870. Epub 2012 Mar 20. Cancer Res. 2012. PMID: 22434430 Free PMC article.

2

HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer.

Chang HR, Nam S, Kook MC, Kim KT, Liu X, Yao H, Jung HR, Lemos R Jr, Seo HH, Park HS, Gim Y, Hong D, Huh I, Kim YW, Tan D, Liu CG, Powis G, Park T, Liang H, Kim YH. Chang HR, et al. Among authors: powis g. Gut. 2016 Jan;65(1):19-32. doi: 10.1136/gutjnl-2014-307918. Epub 2014 Nov 19. Gut. 2016. PMID: 25410163 Free PMC article.

3

The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion.

Koh MY, Lemos R Jr, Liu X, Powis G. Koh MY, et al. Among authors: powis g. Cancer Res. 2011 Jun 1;71(11):4015-27. doi: 10.1158/0008-5472.CAN-10-4142. Epub 2011 Apr 21. Cancer Res. 2011. PMID: 21512133 Free PMC article.

4

The effect of disintegrin-metalloproteinase ADAM9 in gastric cancer progression.

Kim JM, Jeung HC, Rha SY, Yu EJ, Kim TS, Shin YK, Zhang X, Park KH, Park SW, Chung HC, Powis G. Kim JM, et al. Among authors: powis g. Mol Cancer Ther. 2014 Dec;13(12):3074-85. doi: 10.1158/1535-7163.MCT-13-1001. Epub 2014 Oct 24. Mol Cancer Ther. 2014. PMID: 25344581 Free PMC article.

5

A pathway-based approach for identifying biomarkers of tumor progression to trastuzumab-resistant breast cancer.

Nam S, Chang HR, Jung HR, Gim Y, Kim NY, Grailhe R, Seo HR, Park HS, Balch C, Lee J, Park I, Jung SY, Jeong KC, Powis G, Liang H, Lee ES, Ro J, Kim YH. Nam S, et al. Among authors: powis g. Cancer Lett. 2015 Jan 28;356(2 Pt B):880-90. doi: 10.1016/j.canlet.2014.10.038. Epub 2014 Nov 4. Cancer Lett. 2015. PMID: 25449779 Free article.

6

PATHOME: an algorithm for accurately detecting differentially expressed subpathways.

Nam S, Chang HR, Kim KT, Kook MC, Hong D, Kwon CH, Jung HR, Park HS, Powis G, Liang H, Park T, Kim YH. Nam S, et al. Among authors: powis g. Oncogene. 2014 Oct 9;33(41):4941-51. doi: 10.1038/onc.2014.80. Epub 2014 Mar 31. Oncogene. 2014. PMID: 24681952 Free PMC article.

7

Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase.

Kim YH, Coon A, Baker AF, Powis G. Kim YH, et al. Among authors: powis g. Cancer Chemother Pharmacol. 2011 Aug;68(2):405-13. doi: 10.1007/s00280-010-1500-0. Epub 2010 Nov 11. Cancer Chemother Pharmacol. 2011. PMID: 21069338 Free PMC article.

8

Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer.

Chang HR, Nam S, Lee J, Kim JH, Jung HR, Park HS, Park S, Ahn YZ, Huh I, Balch C, Ku JL, Powis G, Park T, Jeong JH, Kim YH. Chang HR, et al. Among authors: powis g. Oncotarget. 2016 Dec 6;7(49):81435-81451. doi: 10.18632/oncotarget.12963. Oncotarget. 2016. PMID: 27806312 Free PMC article.

9

Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems.

Chang HR, Park HS, Ahn YZ, Nam S, Jung HR, Park S, Lee SJ, Balch C, Powis G, Ku JL, Kim YH. Chang HR, et al. Among authors: powis g. BMC Cancer. 2016 Mar 9;16:200. doi: 10.1186/s12885-016-2232-2. BMC Cancer. 2016. PMID: 26955870 Free PMC article.

10

Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.

Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: powis g. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.

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