Howlett GJ - Search Results

1

Small amphipathic molecules modulate secondary structure and amyloid fibril-forming kinetics of Alzheimer disease peptide Aβ(1-42).

Ryan TM, Friedhuber A, Lind M, Howlett GJ, Masters C, Roberts BR. Ryan TM, et al. Among authors: howlett gj. J Biol Chem. 2012 May 11;287(20):16947-54. doi: 10.1074/jbc.M111.321778. Epub 2012 Mar 29. J Biol Chem. 2012. PMID: 22461629 Free PMC article.

2

Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II.

Ryan TM, Howlett GJ, Bailey MF. Ryan TM, et al. Among authors: howlett gj. J Biol Chem. 2008 Dec 12;283(50):35118-28. doi: 10.1074/jbc.M804004200. Epub 2008 Oct 13. J Biol Chem. 2008. PMID: 18852267 Free PMC article.

3

The Role of Lipid in Misfolding and Amyloid Fibril Formation by Apolipoprotein C-II.

Ryan TM, Mok YF, Howlett GJ, Griffin MD. Ryan TM, et al. Among authors: howlett gj. Adv Exp Med Biol. 2015;855:157-74. doi: 10.1007/978-3-319-17344-3_7. Adv Exp Med Biol. 2015. PMID: 26149930 Review.

4

Phospholipids enhance nucleation but not elongation of apolipoprotein C-II amyloid fibrils.

Ryan TM, Teoh CL, Griffin MD, Bailey MF, Schuck P, Howlett GJ. Ryan TM, et al. Among authors: howlett gj. J Mol Biol. 2010 Jun 25;399(5):731-40. doi: 10.1016/j.jmb.2010.04.042. Epub 2010 Apr 28. J Mol Biol. 2010. PMID: 20433849 Free PMC article.

5

Sedimentation velocity analysis of amyloid oligomers and fibrils using fluorescence detection.

Mok YF, Ryan TM, Yang S, Hatters DM, Howlett GJ, Griffin MD. Mok YF, et al. Among authors: howlett gj. Methods. 2011 May;54(1):67-75. doi: 10.1016/j.ymeth.2010.10.004. Epub 2010 Nov 3. Methods. 2011. PMID: 21055469

6

High-affinity amphipathic modulators of amyloid fibril nucleation and elongation.

Ryan TM, Griffin MD, Teoh CL, Ooi J, Howlett GJ. Ryan TM, et al. Among authors: howlett gj. J Mol Biol. 2011 Feb 25;406(3):416-29. doi: 10.1016/j.jmb.2010.12.023. Epub 2010 Dec 23. J Mol Biol. 2011. PMID: 21185302

7

Shear flow induced changes in apolipoprotein C-II conformation and amyloid fibril formation.

Teoh CL, Bekard IB, Asimakis P, Griffin MD, Ryan TM, Dunstan DE, Howlett GJ. Teoh CL, et al. Among authors: howlett gj. Biochemistry. 2011 May 17;50(19):4046-57. doi: 10.1021/bi2002482. Epub 2011 Apr 22. Biochemistry. 2011. PMID: 21476595

8

NBD-labeled phospholipid accelerates apolipoprotein C-II amyloid fibril formation but is not incorporated into mature fibrils.

Ryan TM, Griffin MD, Bailey MF, Schuck P, Howlett GJ. Ryan TM, et al. Among authors: howlett gj. Biochemistry. 2011 Nov 8;50(44):9579-86. doi: 10.1021/bi201192r. Epub 2011 Oct 13. Biochemistry. 2011. PMID: 21985034 Free PMC article.

9

Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils.

Zlatic CO, Mao Y, Ryan TM, Mok YF, Roberts BR, Howlett GJ, Griffin MD. Zlatic CO, et al. Among authors: howlett gj. Biochemistry. 2015 Jun 23;54(24):3831-8. doi: 10.1021/acs.biochem.5b00399. Epub 2015 Jun 12. Biochemistry. 2015. PMID: 26021642

10

Lipid-apolipoprotein interactions in amyloid fibril formation and relevance to atherosclerosis.

Howlett GJ, Ryan TM, Griffin MDW. Howlett GJ, et al. Biochim Biophys Acta Proteins Proteom. 2019 May;1867(5):502-507. doi: 10.1016/j.bbapap.2018.08.010. Epub 2018 Sep 1. Biochim Biophys Acta Proteins Proteom. 2019. PMID: 35818279 Review.

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