Pickarski M - Search Results

1

Evaluation of high-resolution peripheral quantitative computed tomography, finite element analysis and biomechanical testing in a pre-clinical model of osteoporosis: a study with odanacatib treatment in the ovariectomized adult rhesus monkey.

Jayakar RY, Cabal A, Szumiloski J, Sardesai S, Phillips EA, Laib A, Scott BB, Pickarski M, Duong LT, Winkelmann CT, McCracken PJ, Hargreaves R, Hangartner TN, Williams DS. Jayakar RY, et al. Among authors: pickarski m. Bone. 2012 Jun;50(6):1379-88. doi: 10.1016/j.bone.2012.03.017. Epub 2012 Mar 24. Bone. 2012. PMID: 22469953

2

Effects of long term treatment with high doses of odanacatib on bone mass, bone strength, and remodeling/modeling in newly ovariectomized monkeys.

Duong LT, Pickarski M, Cusick T, Chen CM, Zhuo Y, Scott K, Samadfam R, Smith SY, Pennypacker BL. Duong LT, et al. Among authors: pickarski m. Bone. 2016 Jul;88:113-124. doi: 10.1016/j.bone.2016.04.024. Epub 2016 Apr 25. Bone. 2016. PMID: 27126999

3

Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys.

Masarachia PJ, Pennypacker BL, Pickarski M, Scott KR, Wesolowski GA, Smith SY, Samadfam R, Goetzmann JE, Scott BB, Kimmel DB, Duong LT. Masarachia PJ, et al. Among authors: pickarski m. J Bone Miner Res. 2012 Mar;27(3):509-23. doi: 10.1002/jbmr.1475. J Bone Miner Res. 2012. PMID: 22113859 Free article.

4

Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey.

Cusick T, Chen CM, Pennypacker BL, Pickarski M, Kimmel DB, Scott BB, Duong LT. Cusick T, et al. Among authors: pickarski m. J Bone Miner Res. 2012 Mar;27(3):524-37. doi: 10.1002/jbmr.1477. J Bone Miner Res. 2012. PMID: 22113921 Free article.

5

Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis.

Hayami T, Zhuo Y, Wesolowski GA, Pickarski M, Duong LT. Hayami T, et al. Among authors: pickarski m. Bone. 2012 Jun;50(6):1250-9. doi: 10.1016/j.bone.2012.03.025. Epub 2012 Mar 30. Bone. 2012. PMID: 22484689

6

Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: a head-to-head comparison with alendronate.

Williams DS, McCracken PJ, Purcell M, Pickarski M, Mathers PD, Savitz AT, Szumiloski J, Jayakar RY, Somayajula S, Krause S, Brown K, Winkelmann CT, Scott BB, Cook L, Motzel SL, Hargreaves R, Evelhoch JL, Cabal A, Dardzinski BJ, Hangartner TN, Duong LT. Williams DS, et al. Among authors: pickarski m. Bone. 2013 Oct;56(2):489-96. doi: 10.1016/j.bone.2013.06.008. Epub 2013 Jun 24. Bone. 2013. PMID: 23806798

7

Effects of odanacatib on bone matrix mineralization in rhesus monkeys are similar to those of alendronate.

Misof BM, Roschger P, Chen C, Pickarski M, Messmer P, Klaushofer K, Duong LT. Misof BM, et al. Among authors: pickarski m. Bone Rep. 2016 Mar 6;5:62-69. doi: 10.1016/j.bonr.2016.03.001. eCollection 2016 Dec. Bone Rep. 2016. PMID: 28326348 Free PMC article.

8

The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking.

Leung P, Pickarski M, Zhuo Y, Masarachia PJ, Duong LT. Leung P, et al. Among authors: pickarski m. Bone. 2011 Oct;49(4):623-35. doi: 10.1016/j.bone.2011.06.014. Epub 2011 Jun 22. Bone. 2011. PMID: 21718816

9

Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis.

Hayami T, Pickarski M, Zhuo Y, Wesolowski GA, Rodan GA, Duong LT. Hayami T, et al. Among authors: pickarski m. Bone. 2006 Feb;38(2):234-43. doi: 10.1016/j.bone.2005.08.007. Epub 2005 Sep 26. Bone. 2006. PMID: 16185945

10

Efficacy of a cathepsin K inhibitor in a preclinical model for prevention and treatment of breast cancer bone metastasis.

Duong LT, Wesolowski GA, Leung P, Oballa R, Pickarski M. Duong LT, et al. Among authors: pickarski m. Mol Cancer Ther. 2014 Dec;13(12):2898-909. doi: 10.1158/1535-7163.MCT-14-0253. Epub 2014 Sep 23. Mol Cancer Ther. 2014. PMID: 25249554

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