Grigorian A - Search Results

1

Pathogenesis of multiple sclerosis via environmental and genetic dysregulation of N-glycosylation.

Grigorian A, Mkhikian H, Li CF, Newton BL, Zhou RW, Demetriou M. Grigorian A, et al. Semin Immunopathol. 2012 May;34(3):415-24. doi: 10.1007/s00281-012-0307-y. Epub 2012 Apr 11. Semin Immunopathol. 2012. PMID: 22488447 Free PMC article. Review.

2

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.

Mkhikian H, Grigorian A, Li CF, Chen HL, Newton B, Zhou RW, Beeton C, Torossian S, Tatarian GG, Lee SU, Lau K, Walker E, Siminovitch KA, Chandy KG, Yu Z, Dennis JW, Demetriou M. Mkhikian H, et al. Among authors: grigorian a. Nat Commun. 2011;2:334. doi: 10.1038/ncomms1333. Nat Commun. 2011. PMID: 21629267 Free PMC article.

3

Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation.

Grigorian A, Mkhikian H, Demetriou M. Grigorian A, et al. Ann N Y Acad Sci. 2012 Apr;1253:49-57. doi: 10.1111/j.1749-6632.2011.06391.x. Epub 2012 Jan 30. Ann N Y Acad Sci. 2012. PMID: 22288682 Free PMC article. Review.

4

N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca²⁺ signaling.

Zhou RW, Mkhikian H, Grigorian A, Hong A, Chen D, Arakelyan A, Demetriou M. Zhou RW, et al. Among authors: grigorian a. Nat Immunol. 2014 Nov;15(11):1038-45. doi: 10.1038/ni.3007. Epub 2014 Sep 28. Nat Immunol. 2014. PMID: 25263124

5

Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis.

Grigorian A, Lee SU, Tian W, Chen IJ, Gao G, Mendelsohn R, Dennis JW, Demetriou M. Grigorian A, et al. J Biol Chem. 2007 Jul 6;282(27):20027-35. doi: 10.1074/jbc.M701890200. Epub 2007 May 8. J Biol Chem. 2007. PMID: 17488719 Free article.

6

N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration.

Lee SU, Grigorian A, Pawling J, Chen IJ, Gao G, Mozaffar T, McKerlie C, Demetriou M. Lee SU, et al. Among authors: grigorian a. J Biol Chem. 2007 Nov 16;282(46):33725-33734. doi: 10.1074/jbc.M704839200. Epub 2007 Sep 13. J Biol Chem. 2007. PMID: 17855338 Free article.

7

T-cell growth, cell surface organization, and the galectin-glycoprotein lattice.

Grigorian A, Torossian S, Demetriou M. Grigorian A, et al. Immunol Rev. 2009 Jul;230(1):232-46. doi: 10.1111/j.1600-065X.2009.00796.x. Immunol Rev. 2009. PMID: 19594640 Free PMC article. Review.

8

T cell receptor signaling co-regulates multiple Golgi genes to enhance N-glycan branching.

Chen HL, Li CF, Grigorian A, Tian W, Demetriou M. Chen HL, et al. Among authors: grigorian a. J Biol Chem. 2009 Nov 20;284(47):32454-61. doi: 10.1074/jbc.M109.023630. Epub 2009 Aug 25. J Biol Chem. 2009. PMID: 19706602 Free PMC article.

9

Manipulating cell surface glycoproteins by targeting N-glycan-galectin interactions.

Grigorian A, Demetriou M. Grigorian A, et al. Methods Enzymol. 2010;480:245-66. doi: 10.1016/S0076-6879(10)80012-6. Methods Enzymol. 2010. PMID: 20816213 Review.

10

N-acetylglucosamine inhibits T-helper 1 (Th1)/T-helper 17 (Th17) cell responses and treats experimental autoimmune encephalomyelitis.

Grigorian A, Araujo L, Naidu NN, Place DJ, Choudhury B, Demetriou M. Grigorian A, et al. J Biol Chem. 2011 Nov 18;286(46):40133-41. doi: 10.1074/jbc.M111.277814. Epub 2011 Sep 29. J Biol Chem. 2011. PMID: 21965673 Free PMC article.

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