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Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.
Tang M, Zhang X, Li Y, Guan Y, Ai X, Szeto C, Nakayama H, Zhang H, Ge S, Molkentin JD, Houser SR, Chen X. Tang M, et al. Among authors: chen x. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H519-28. doi: 10.1152/ajpheart.00265.2010. Epub 2010 Jun 11. Am J Physiol Heart Circ Physiol. 2010. PMID: 20543081 Free PMC article.
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Raake PW, Zhang X, Vinge LE, Brinks H, Gao E, Jaleel N, Li Y, Tang M, Most P, Dorn GW 2nd, Houser SR, Katus HA, Chen X, Koch WJ. Raake PW, et al. Among authors: chen x. Circulation. 2012 May 1;125(17):2108-18. doi: 10.1161/CIRCULATIONAHA.111.044255. Epub 2012 Apr 10. Circulation. 2012. PMID: 22496128 Free PMC article.
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling.
Zhang X, Szeto C, Gao E, Tang M, Jin J, Fu Q, Makarewich C, Ai X, Li Y, Tang A, Wang J, Gao H, Wang F, Ge XJ, Kunapuli SP, Zhou L, Zeng C, Xiang KY, Chen X. Zhang X, et al. Among authors: chen x. Circ Res. 2013 Feb 1;112(3):498-509. doi: 10.1161/CIRCRESAHA.112.273896. Epub 2012 Oct 25. Circ Res. 2013. PMID: 23104882 Free PMC article.
Compartmentalization of β-adrenergic signals in cardiomyocytes.
Fu Q, Chen X, Xiang YK. Fu Q, et al. Among authors: chen x. Trends Cardiovasc Med. 2013 Oct;23(7):250-6. doi: 10.1016/j.tcm.2013.02.001. Epub 2013 Mar 23. Trends Cardiovasc Med. 2013. PMID: 23528751 Free PMC article. Review.
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