Madani N - Search Results

1

Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors.

LaLonde JM, Kwon YD, Jones DM, Sun AW, Courter JR, Soeta T, Kobayashi T, Princiotto AM, Wu X, Schön A, Freire E, Kwong PD, Mascola JR, Sodroski J, Madani N, Smith AB 3rd. LaLonde JM, et al. Among authors: madani n. J Med Chem. 2012 May 10;55(9):4382-96. doi: 10.1021/jm300265j. Epub 2012 Apr 23. J Med Chem. 2012. PMID: 22497421 Free PMC article.

2

Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression.

LaBonte JA, Madani N, Sodroski J. LaBonte JA, et al. Among authors: madani n. J Virol. 2003 Jun;77(12):6645-59. doi: 10.1128/jvi.77.12.6645-6659.2003. J Virol. 2003. PMID: 12767984 Free PMC article.

3

Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions.

Biorn AC, Cocklin S, Madani N, Si Z, Ivanovic T, Samanen J, Van Ryk DI, Pantophlet R, Burton DR, Freire E, Sodroski J, Chaiken IM. Biorn AC, et al. Among authors: madani n. Biochemistry. 2004 Feb 24;43(7):1928-38. doi: 10.1021/bi035088i. Biochemistry. 2004. PMID: 14967033

4

Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155.

Madani N, Perdigoto AL, Srinivasan K, Cox JM, Chruma JJ, LaLonde J, Head M, Smith AB 3rd, Sodroski JG. Madani N, et al. J Virol. 2004 Apr;78(7):3742-52. doi: 10.1128/jvi.78.7.3742-3752.2004. J Virol. 2004. PMID: 15016894 Free PMC article.

5

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.

Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB 3rd, Sodroski JG. Si Z, et al. Among authors: madani n. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5036-41. doi: 10.1073/pnas.0307953101. Epub 2004 Mar 29. Proc Natl Acad Sci U S A. 2004. PMID: 15051887 Free PMC article.

6

Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody.

Xiang SH, Farzan M, Si Z, Madani N, Wang L, Rosenberg E, Robinson J, Sodroski J. Xiang SH, et al. Among authors: madani n. J Virol. 2005 May;79(10):6068-77. doi: 10.1128/JVI.79.10.6068-6077.2005. J Virol. 2005. PMID: 15857992 Free PMC article.

7

Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors.

Choi WT, Tian S, Dong CZ, Kumar S, Liu D, Madani N, An J, Sodroski JG, Huang Z. Choi WT, et al. Among authors: madani n. J Virol. 2005 Dec;79(24):15398-404. doi: 10.1128/JVI.79.24.15398-15404.2005. J Virol. 2005. PMID: 16306611 Free PMC article.

8

Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand.

Dong CZ, Kumar S, Choi WT, Madani N, Tian S, An J, Sodroski JG, Huang Z. Dong CZ, et al. Among authors: madani n. J Med Chem. 2005 Dec 15;48(25):7923-4. doi: 10.1021/jm050829u. J Med Chem. 2005. PMID: 16335916

9

SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development.

Kumar S, Choi WT, Dong CZ, Madani N, Tian S, Liu D, Wang Y, Pesavento J, Wang J, Fan X, Yuan J, Fritzsche WR, An J, Sodroski JG, Richman DD, Huang Z. Kumar S, et al. Among authors: madani n. Chem Biol. 2006 Jan;13(1):69-79. doi: 10.1016/j.chembiol.2005.10.012. Chem Biol. 2006. PMID: 16426973

10

Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry.

Madani N, Hubicki AM, Perdigoto AL, Springer M, Sodroski J. Madani N, et al. J Virol. 2007 Jan;81(2):532-8. doi: 10.1128/JVI.01079-06. Epub 2006 Aug 30. J Virol. 2007. PMID: 16943294 Free PMC article.

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