Dhooghe B - Search Results

1

Immunomodulatory activity of vardenafil on induced lung inflammation in cystic fibrosis mice.

Lubamba B, Huaux F, Lebacq J, Marbaix E, Dhooghe B, Panin N, Wallemacq P, Leal T. Lubamba B, et al. Among authors: dhooghe b. J Cyst Fibros. 2012 Jul;11(4):266-73. doi: 10.1016/j.jcf.2012.03.003. Epub 2012 Apr 12. J Cyst Fibros. 2012. PMID: 22503062 Free article.

2

Cystic fibrosis: insight into CFTR pathophysiology and pharmacotherapy.

Lubamba B, Dhooghe B, Noel S, Leal T. Lubamba B, et al. Among authors: dhooghe b. Clin Biochem. 2012 Oct;45(15):1132-44. doi: 10.1016/j.clinbiochem.2012.05.034. Epub 2012 Jun 12. Clin Biochem. 2012. PMID: 22698459 Review.

3

Dysregulated proinflammatory and fibrogenic phenotype of fibroblasts in cystic fibrosis.

Huaux F, Noel S, Dhooghe B, Panin N, Lo Re S, Lison D, Wallemacq P, Marbaix E, Scholte BJ, Lebecque P, Leal T. Huaux F, et al. Among authors: dhooghe b. PLoS One. 2013 May 29;8(5):e64341. doi: 10.1371/journal.pone.0064341. Print 2013. PLoS One. 2013. PMID: 23734196 Free PMC article.

4

Correction of chloride transport and mislocalization of CFTR protein by vardenafil in the gastrointestinal tract of cystic fibrosis mice.

Dhooghe B, Noël S, Bouzin C, Behets-Wydemans G, Leal T. Dhooghe B, et al. PLoS One. 2013 Oct 24;8(10):e77314. doi: 10.1371/journal.pone.0077314. eCollection 2013. PLoS One. 2013. PMID: 24204804 Free PMC article.

5

Lung inflammation in cystic fibrosis: pathogenesis and novel therapies.

Dhooghe B, Noël S, Huaux F, Leal T. Dhooghe B, et al. Clin Biochem. 2014 May;47(7-8):539-46. doi: 10.1016/j.clinbiochem.2013.12.020. Epub 2013 Dec 29. Clin Biochem. 2014. PMID: 24380764 Review.

6

Vardenafil reduces macrophage pro-inflammatory overresponses in cystic fibrosis through PDE5- and CFTR-dependent mechanisms.

Noel S, Panin N, Beka M, Dhooghe B, Huaux F, Leal T. Noel S, et al. Among authors: dhooghe b. Clin Sci (Lond). 2017 Jun 1;131(11):1107-1121. doi: 10.1042/CS20160749. Epub 2017 Feb 14. Clin Sci (Lond). 2017. PMID: 28196856

7

Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells.

Dhooghe B, Bouzin C, Mottais A, Hermans E, Delion M, Panin N, Noel S, Leal T. Dhooghe B, et al. Biol Open. 2020 Aug 25;9(8):bio053116. doi: 10.1242/bio.053116. Biol Open. 2020. PMID: 32747447 Free PMC article.

8

PDE5 Inhibitors as Potential Tools in the Treatment of Cystic Fibrosis.

Noel S, Dhooghe B, Leal T. Noel S, et al. Among authors: dhooghe b. Front Pharmacol. 2012 Sep 18;3:167. doi: 10.3389/fphar.2012.00167. eCollection 2012. Front Pharmacol. 2012. PMID: 23024633 Free PMC article.

9

Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice.

Dhooghe B, Bouckaert C, Capron A, Wallemacq P, Leal T, Noel S. Dhooghe B, et al. Biol Open. 2015 Jun 19;4(7):929-36. doi: 10.1242/bio.010967. Biol Open. 2015. PMID: 26092868 Free PMC article.

10

Strategies in early clinical development for the treatment of basic defects of cystic fibrosis.

Dhooghe B, Haaf JB, Noel S, Leal T. Dhooghe B, et al. Expert Opin Investig Drugs. 2016;25(4):423-36. doi: 10.1517/13543784.2016.1154041. Epub 2016 Mar 7. Expert Opin Investig Drugs. 2016. PMID: 26878157 Review.

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