Larochelle S - Search Results

1

Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition.

St Amour CV, Sansó M, Bösken CA, Lee KM, Larochelle S, Zhang C, Shokat KM, Geyer M, Fisher RP. St Amour CV, et al. Among authors: larochelle s. Mol Cell Biol. 2012 Jul;32(13):2372-83. doi: 10.1128/MCB.06657-11. Epub 2012 Apr 16. Mol Cell Biol. 2012. PMID: 22508988 Free PMC article.

2

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II.

Glover-Cutter K, Larochelle S, Erickson B, Zhang C, Shokat K, Fisher RP, Bentley DL. Glover-Cutter K, et al. Among authors: larochelle s. Mol Cell Biol. 2009 Oct;29(20):5455-64. doi: 10.1128/MCB.00637-09. Epub 2009 Aug 10. Mol Cell Biol. 2009. PMID: 19667075 Free PMC article.

3

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.

Larochelle S, Amat R, Glover-Cutter K, Sansó M, Zhang C, Allen JJ, Shokat KM, Bentley DL, Fisher RP. Larochelle S, et al. Nat Struct Mol Biol. 2012 Nov;19(11):1108-15. doi: 10.1038/nsmb.2399. Epub 2012 Oct 14. Nat Struct Mol Biol. 2012. PMID: 23064645 Free PMC article.

4

A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression.

Schachter MM, Merrick KA, Larochelle S, Hirschi A, Zhang C, Shokat KM, Rubin SM, Fisher RP. Schachter MM, et al. Among authors: larochelle s. Mol Cell. 2013 Apr 25;50(2):250-60. doi: 10.1016/j.molcel.2013.04.003. Mol Cell. 2013. PMID: 23622515 Free PMC article.

5

P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.

Sansó M, Levin RS, Lipp JJ, Wang VY, Greifenberg AK, Quezada EM, Ali A, Ghosh A, Larochelle S, Rana TM, Geyer M, Tong L, Shokat KM, Fisher RP. Sansó M, et al. Among authors: larochelle s. Genes Dev. 2016 Jan 1;30(1):117-31. doi: 10.1101/gad.269589.115. Genes Dev. 2016. PMID: 26728557 Free PMC article.

6

Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.

Larochelle S, Batliner J, Gamble MJ, Barboza NM, Kraybill BC, Blethrow JD, Shokat KM, Fisher RP. Larochelle S, et al. Nat Struct Mol Biol. 2006 Jan;13(1):55-62. doi: 10.1038/nsmb1028. Epub 2005 Dec 4. Nat Struct Mol Biol. 2006. PMID: 16327805

7

The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity.

Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP. Wohlbold L, et al. Among authors: larochelle s. Cell Cycle. 2006 Mar;5(5):546-54. doi: 10.4161/cc.5.5.2541. Epub 2006 Mar 1. Cell Cycle. 2006. PMID: 16552187

8

Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, Zhang C, Shokat KM, Jallepalli PV, Fisher RP. Larochelle S, et al. Mol Cell. 2007 Mar 23;25(6):839-50. doi: 10.1016/j.molcel.2007.02.003. Mol Cell. 2007. PMID: 17386261 Free PMC article.

9

Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.

Sordet O, Larochelle S, Nicolas E, Stevens EV, Zhang C, Shokat KM, Fisher RP, Pommier Y. Sordet O, et al. Among authors: larochelle s. J Mol Biol. 2008 Sep 5;381(3):540-9. doi: 10.1016/j.jmb.2008.06.028. Epub 2008 Jun 17. J Mol Biol. 2008. PMID: 18588899 Free PMC article.

10

Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells.

Merrick KA, Larochelle S, Zhang C, Allen JJ, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: larochelle s. Mol Cell. 2008 Dec 5;32(5):662-72. doi: 10.1016/j.molcel.2008.10.022. Mol Cell. 2008. PMID: 19061641 Free PMC article.

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