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NDR functions as a physiological YAP1 kinase in the intestinal epithelium.
Zhang L, Tang F, Terracciano L, Hynx D, Kohler R, Bichet S, Hess D, Cron P, Hemmings BA, Hergovich A, Schmitz-Rohmer D. Zhang L, et al. Among authors: hergovich a. Curr Biol. 2015 Feb 2;25(3):296-305. doi: 10.1016/j.cub.2014.11.054. Epub 2015 Jan 15. Curr Biol. 2015. PMID: 25601544 Free PMC article.
The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility.
Tang F, Gill J, Ficht X, Barthlott T, Cornils H, Schmitz-Rohmer D, Hynx D, Zhou D, Zhang L, Xue G, Grzmil M, Yang Z, Hergovich A, Hollaender GA, Stein JV, Hemmings BA, Matthias P. Tang F, et al. Among authors: hergovich a. Sci Signal. 2015 Oct 6;8(397):ra100. doi: 10.1126/scisignal.aab2425. Sci Signal. 2015. PMID: 26443704
73 results