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Mice expressing activated PI3K rapidly develop advanced colon cancer.
Leystra AA, Deming DA, Zahm CD, Farhoud M, Olson TJ, Hadac JN, Nettekoven LA, Albrecht DM, Clipson L, Sullivan R, Washington MK, Torrealba JR, Weichert JP, Halberg RB. Leystra AA, et al. Among authors: clipson l. Cancer Res. 2012 Jun 15;72(12):2931-6. doi: 10.1158/0008-5472.CAN-11-4097. Epub 2012 Apr 23. Cancer Res. 2012. PMID: 22525701 Free PMC article.
PIK3CA and APC mutations are synergistic in the development of intestinal cancers.
Deming DA, Leystra AA, Nettekoven L, Sievers C, Miller D, Middlebrooks M, Clipson L, Albrecht D, Bacher J, Washington MK, Weichert J, Halberg RB. Deming DA, et al. Among authors: clipson l. Oncogene. 2014 Apr 24;33(17):2245-54. doi: 10.1038/onc.2013.167. Epub 2013 May 27. Oncogene. 2014. PMID: 23708654 Free PMC article.
Clonal structure of carcinogen-induced intestinal tumors in mice.
Thliveris AT, Clipson L, White A, Waggoner J, Plesh L, Skinner BL, Zahm CD, Sullivan R, Dove WF, Newton MA, Halberg RB. Thliveris AT, et al. Among authors: clipson l. Cancer Prev Res (Phila). 2011 Jun;4(6):916-23. doi: 10.1158/1940-6207.CAPR-11-0022. Cancer Prev Res (Phila). 2011. PMID: 21636550 Free PMC article.
mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.
Deming DA, Leystra AA, Farhoud M, Nettekoven L, Clipson L, Albrecht D, Washington MK, Sullivan R, Weichert JP, Halberg RB. Deming DA, et al. Among authors: clipson l. PLoS One. 2013 Apr 9;8(4):e60709. doi: 10.1371/journal.pone.0060709. Print 2013. PLoS One. 2013. PMID: 23593290 Free PMC article.
Transformation of epithelial cells through recruitment leads to polyclonal intestinal tumors.
Thliveris AT, Schwefel B, Clipson L, Plesh L, Zahm CD, Leystra AA, Washington MK, Sullivan R, Deming DA, Newton MA, Halberg RB. Thliveris AT, et al. Among authors: clipson l. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11523-8. doi: 10.1073/pnas.1303064110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798428 Free PMC article.
Dynamic tumor growth patterns in a novel murine model of colorectal cancer.
Paul Olson TJ, Hadac JN, Sievers CK, Leystra AA, Deming DA, Zahm CD, Albrecht DM, Nomura A, Nettekoven LA, Plesh LK, Clipson L, Sullivan R, Newton MA, Schelman WR, Halberg RB. Paul Olson TJ, et al. Among authors: clipson l. Cancer Prev Res (Phila). 2014 Jan;7(1):105-13. doi: 10.1158/1940-6207.CAPR-13-0163. Epub 2013 Nov 6. Cancer Prev Res (Phila). 2014. PMID: 24196829 Free PMC article.
Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence.
Hadac JN, Leystra AA, Paul Olson TJ, Maher ME, Payne SN, Yueh AE, Schwartz AR, Albrecht DM, Clipson L, Pasch CA, Matkowskyj KA, Halberg RB, Deming DA. Hadac JN, et al. Among authors: clipson l. Cancer Prev Res (Phila). 2015 Oct;8(10):952-61. doi: 10.1158/1940-6207.CAPR-15-0003. Epub 2015 Aug 14. Cancer Prev Res (Phila). 2015. PMID: 26276752 Free PMC article.
Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.
Yueh AE, Payne SN, Leystra AA, Van De Hey DR, Foley TM, Pasch CA, Clipson L, Matkowskyj KA, Deming DA. Yueh AE, et al. Among authors: clipson l. PLoS One. 2016 Feb 10;11(2):e0148730. doi: 10.1371/journal.pone.0148730. eCollection 2016. PLoS One. 2016. PMID: 26863299 Free PMC article.
Advanced Intestinal Cancers often Maintain a Multi-Ancestral Architecture.
Zahm CD, Szulczewski JM, Leystra AA, Paul Olson TJ, Clipson L, Albrecht DM, Middlebrooks M, Thliveris AT, Matkowskyj KA, Washington MK, Newton MA, Eliceiri KW, Halberg RB. Zahm CD, et al. Among authors: clipson l. PLoS One. 2016 Feb 26;11(2):e0150170. doi: 10.1371/journal.pone.0150170. eCollection 2016. PLoS One. 2016. PMID: 26919712 Free PMC article.
53 results