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New adamantane derivatives with sigma affinity and antiproliferative activity.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Margarita P, Georgakopoulou S, Zaniou A, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A. Riganas S, et al. Med Chem. 2012 Jul;8(4):569-86. doi: 10.2174/157340612801216201. Med Chem. 2012. PMID: 22530894
Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Bourguignon JJ, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Pondiki S, Vamvakides A. Riganas S, et al. Bioorg Med Chem. 2012 May 15;20(10):3323-31. doi: 10.1016/j.bmc.2012.03.038. Epub 2012 Mar 24. Bioorg Med Chem. 2012. PMID: 22512908
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A. Riganas S, et al. J Med Chem. 2012 Nov 26;55(22):10241-61. doi: 10.1021/jm3013008. Epub 2012 Nov 9. J Med Chem. 2012. PMID: 23094992