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New adamantane derivatives with sigma affinity and antiproliferative activity.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Margarita P, Georgakopoulou S, Zaniou A, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A. Riganas S, et al. Among authors: vamvakides a. Med Chem. 2012 Jul;8(4):569-86. doi: 10.2174/157340612801216201. Med Chem. 2012. PMID: 22530894
Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Bourguignon JJ, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Pondiki S, Vamvakides A. Riganas S, et al. Among authors: vamvakides a. Bioorg Med Chem. 2012 May 15;20(10):3323-31. doi: 10.1016/j.bmc.2012.03.038. Epub 2012 Mar 24. Bioorg Med Chem. 2012. PMID: 22512908
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
Riganas S, Papanastasiou I, Foscolos GB, Tsotinis A, Serin G, Mirjolet JF, Dimas K, Kourafalos VN, Eleutheriades A, Moutsos VI, Khan H, Georgakopoulou S, Zaniou A, Prassa M, Theodoropoulou M, Mantelas A, Pondiki S, Vamvakides A. Riganas S, et al. Among authors: vamvakides a. J Med Chem. 2012 Nov 26;55(22):10241-61. doi: 10.1021/jm3013008. Epub 2012 Nov 9. J Med Chem. 2012. PMID: 23094992
Blockade of Tau hyperphosphorylation and Aβ₁₋₄₂ generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and σ₁ receptor agonist, in a nontransgenic mouse model of Alzheimer's disease.
Lahmy V, Meunier J, Malmström S, Naert G, Givalois L, Kim SH, Villard V, Vamvakides A, Maurice T. Lahmy V, et al. Among authors: vamvakides a. Neuropsychopharmacology. 2013 Aug;38(9):1706-23. doi: 10.1038/npp.2013.70. Epub 2013 Mar 14. Neuropsychopharmacology. 2013. PMID: 23493042 Free PMC article.
71 results