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Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation.
Basu NK, Kubota S, Meselhy MR, Ciotti M, Chowdhury B, Hartori M, Owens IS. Basu NK, et al. Among authors: owens is. J Biol Chem. 2004 Jul 2;279(27):28320-9. doi: 10.1074/jbc.M401396200. Epub 2004 Apr 26. J Biol Chem. 2004. PMID: 15117964 Free article.
S., Kole, L., Mitra, P. S., Cho, J. W., and Owens, I. S. (2004) J. Biol. Chem. 279, 1429-1441), UGT1A10 metabolized estrogens and their derivatives, whereas UGT1A1, -1A3, -1A7, and -1A8 differentially exhibited reduced activity toward the same. ...In summary, our results s …
S., Kole, L., Mitra, P. S., Cho, J. W., and Owens, I. S. (2004) J. Biol. Chem. 279, 1429-1441), UGT1A10 metabolized estrogens and the …
Phosphorylation of a UDP-glucuronosyltransferase regulates substrate specificity.
Basu NK, Kovarova M, Garza A, Kubota S, Saha T, Mitra PS, Banerjee R, Rivera J, Owens IS. Basu NK, et al. Among authors: owens is. Proc Natl Acad Sci U S A. 2005 May 3;102(18):6285-90. doi: 10.1073/pnas.0407872102. Epub 2005 Apr 21. Proc Natl Acad Sci U S A. 2005. PMID: 15845768 Free PMC article.
78 results