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Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer.
Wang JG, Geddings JE, Aleman MM, Cardenas JC, Chantrathammachart P, Williams JC, Kirchhofer D, Bogdanov VY, Bach RR, Rak J, Church FC, Wolberg AS, Pawlinski R, Key NS, Yeh JJ, Mackman N. Wang JG, et al. Among authors: mackman n. Blood. 2012 Jun 7;119(23):5543-52. doi: 10.1182/blood-2012-01-402156. Epub 2012 Apr 30. Blood. 2012. PMID: 22547577 Free PMC article.
Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.
Pawlinski R, Fernandes A, Kehrle B, Pedersen B, Parry G, Erlich J, Pyo R, Gutstein D, Zhang J, Castellino F, Melis E, Carmeliet P, Baretton G, Luther T, Taubman M, Rosen E, Mackman N. Pawlinski R, et al. Among authors: mackman n. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15333-8. doi: 10.1073/pnas.242501899. Epub 2002 Nov 8. Proc Natl Acad Sci U S A. 2002. PMID: 12426405 Free PMC article.
PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.
Schabbauer G, Tencati M, Pedersen B, Pawlinski R, Mackman N. Schabbauer G, et al. Among authors: mackman n. Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1963-9. doi: 10.1161/01.ATV.0000143096.15099.ce. Epub 2004 Aug 19. Arterioscler Thromb Vasc Biol. 2004. PMID: 15319270
527 results