Eltit JM - Search Results

1

Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.

Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Eltit JM, et al. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7923-8. doi: 10.1073/pnas.1119207109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547813 Free PMC article.

2

Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak.

Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR. Eltit JM, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7046-51. doi: 10.1073/pnas.1018380108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482776 Free PMC article.

3

RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes.

Eltit JM, Yang T, Li H, Molinski TF, Pessah IN, Allen PD, Lopez JR. Eltit JM, et al. J Biol Chem. 2010 Apr 30;285(18):13781-7. doi: 10.1074/jbc.M110.107300. Epub 2010 Mar 5. J Biol Chem. 2010. PMID: 20207743 Free PMC article.

4

A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.

Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR. Estève E, et al. Among authors: eltit jm. J Gen Physiol. 2010 Jun;135(6):619-28. doi: 10.1085/jgp.200910328. Epub 2010 May 17. J Gen Physiol. 2010. PMID: 20479110 Free PMC article.

5

Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.

Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF. Eltit JM, et al. J Biol Chem. 2010 Dec 3;285(49):38453-62. doi: 10.1074/jbc.M110.164525. Epub 2010 Oct 6. J Biol Chem. 2010. PMID: 20926377 Free PMC article.

6

Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes.

Li H, Ding X, Lopez JR, Takeshima H, Ma J, Allen PD, Eltit JM. Li H, et al. Among authors: eltit jm. J Biol Chem. 2010 Dec 10;285(50):39171-9. doi: 10.1074/jbc.M110.149690. Epub 2010 Oct 11. J Biol Chem. 2010. PMID: 20937810 Free PMC article.

7

Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle.

Altamirano F, Eltit JM, Robin G, Linares N, Ding X, Pessah IN, Allen PD, López JR. Altamirano F, et al. Among authors: eltit jm. J Biol Chem. 2014 Jul 4;289(27):19180-90. doi: 10.1074/jbc.M114.550764. Epub 2014 May 20. J Biol Chem. 2014. PMID: 24847052 Free PMC article.

8

A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels.

Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG. Bannister RA, et al. Among authors: eltit jm. J Gen Physiol. 2010 Jun;135(6):629-40. doi: 10.1085/jgp.200910329. Epub 2010 May 17. J Gen Physiol. 2010. PMID: 20479108 Free PMC article.

9

Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction.

Eltit JM, Szpyt J, Li H, Allen PD, Perez CF. Eltit JM, et al. Cell Calcium. 2011 Feb;49(2):128-35. doi: 10.1016/j.ceca.2011.01.005. Cell Calcium. 2011. PMID: 21310482 Free PMC article.

10

Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia.

Eltit JM, Ding X, Pessah IN, Allen PD, Lopez JR. Eltit JM, et al. FASEB J. 2013 Mar;27(3):991-1000. doi: 10.1096/fj.12-218354. Epub 2012 Nov 16. FASEB J. 2013. PMID: 23159934 Free PMC article.

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