Pitts TM - Search Results

1

Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib.

Arcaroli JJ, Quackenbush KS, Powell RW, Pitts TM, Spreafico A, Varella-Garcia M, Bemis L, Tan AC, Reinemann JM, Touban BM, Dasari A, Eckhardt SG, Messersmith WA. Arcaroli JJ, et al. Among authors: pitts tm. Clin Cancer Res. 2012 May 1;18(9):2704-14. doi: 10.1158/1078-0432.CCR-11-3167. Clin Cancer Res. 2012. PMID: 22553375 Free PMC article.

2

Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.

Arcaroli J, Yang KY, Yum HK, Kupfner J, Pitts TM, Park JS, Strassheim D, Abraham E. Arcaroli J, et al. Among authors: pitts tm. J Leukoc Biol. 2002 Sep;72(3):571-9. J Leukoc Biol. 2002. PMID: 12223526

3

Activation of gene expression in human neutrophils by high mobility group box 1 protein.

Park JS, Arcaroli J, Yum HK, Yang H, Wang H, Yang KY, Choe KH, Strassheim D, Pitts TM, Tracey KJ, Abraham E. Park JS, et al. Among authors: pitts tm. Am J Physiol Cell Physiol. 2003 Apr;284(4):C870-9. doi: 10.1152/ajpcell.00322.2002. Am J Physiol Cell Physiol. 2003. PMID: 12620891 Free article.

4

The farnesyl transferase inhibitor, tipifarnib, is a potent inhibitor of the MDR1 gene product, P-glycoprotein, and demonstrates significant cytotoxic synergism against human leukemia cell lines.

Medeiros BC, Landau HJ, Morrow M, Lockerbie RO, Pitts T, Eckhardt SG. Medeiros BC, et al. Leukemia. 2007 Apr;21(4):739-46. doi: 10.1038/sj.leu.2404539. Epub 2007 Feb 1. Leukemia. 2007. PMID: 17268526

5

Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models.

Pitts TM, Morrow M, Kaufman SA, Tentler JJ, Eckhardt SG. Pitts TM, et al. Mol Cancer Ther. 2009 Feb;8(2):342-9. doi: 10.1158/1535-7163.MCT-08-0534. Epub 2009 Jan 27. Mol Cancer Ther. 2009. PMID: 19174560 Free PMC article.

6

Targeting vascular endothelial growth factor receptor-1 and -3 with cediranib (AZD2171): effects on migration and invasion of gastrointestinal cancer cell lines.

Morelli MP, Brown AM, Pitts TM, Tentler JJ, Ciardiello F, Ryan A, Jürgensmeier JM, Eckhardt SG. Morelli MP, et al. Among authors: pitts tm. Mol Cancer Ther. 2009 Sep;8(9):2546-58. doi: 10.1158/1535-7163.MCT-09-0380. Epub 2009 Sep 15. Mol Cancer Ther. 2009. PMID: 19755510 Free PMC article.

7

Assessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models.

Tentler JJ, Bradshaw-Pierce EL, Serkova NJ, Hasebroock KM, Pitts TM, Diamond JR, Fletcher GC, Bray MR, Eckhardt SG. Tentler JJ, et al. Among authors: pitts tm. Clin Cancer Res. 2010 Jun 1;16(11):2989-2998. doi: 10.1158/1078-0432.CCR-10-0325. Epub 2010 Apr 20. Clin Cancer Res. 2010. PMID: 20406842 Free PMC article.

8

Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study.

Mouchawar J, Korch C, Byers T, Pitts TM, Li E, McCredie MR, Giles GG, Hopper JL, Southey MC. Mouchawar J, et al. Among authors: pitts tm. Cancer Res. 2010 Jun 15;70(12):4795-800. doi: 10.1158/0008-5472.CAN-09-0851. Epub 2010 May 25. Cancer Res. 2010. PMID: 20501846 Free PMC article.

9

Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.

Pitts TM, Tan AC, Kulikowski GN, Tentler JJ, Brown AM, Flanigan SA, Leong S, Coldren CD, Hirsch FR, Varella-Garcia M, Korch C, Eckhardt SG. Pitts TM, et al. Clin Cancer Res. 2010 Jun 15;16(12):3193-204. doi: 10.1158/1078-0432.CCR-09-3191. Epub 2010 Jun 8. Clin Cancer Res. 2010. PMID: 20530704 Free PMC article.

10

Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.

Tentler JJ, Nallapareddy S, Tan AC, Spreafico A, Pitts TM, Morelli MP, Selby HM, Kachaeva MI, Flanigan SA, Kulikowski GN, Leong S, Arcaroli JJ, Messersmith WA, Eckhardt SG. Tentler JJ, et al. Among authors: pitts tm. Mol Cancer Ther. 2010 Dec;9(12):3351-62. doi: 10.1158/1535-7163.MCT-10-0376. Epub 2010 Oct 5. Mol Cancer Ther. 2010. PMID: 20923857 Free PMC article.

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