Jeong LS - Search Results

1

The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth.

Luo Z, Yu G, Lee HW, Li L, Wang L, Yang D, Pan Y, Ding C, Qian J, Wu L, Chu Y, Yi J, Wang X, Sun Y, Jeong LS, Liu J, Jia L. Luo Z, et al. Among authors: jeong ls. Cancer Res. 2012 Jul 1;72(13):3360-71. doi: 10.1158/0008-5472.CAN-12-0388. Epub 2012 May 4. Cancer Res. 2012. PMID: 22562464

2

Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety.

Gao ZG, Joshi BV, Klutz AM, Kim SK, Lee HW, Kim HO, Jeong LS, Jacobson KA. Gao ZG, et al. Among authors: jeong ls. Bioorg Med Chem Lett. 2006 Feb;16(3):596-601. doi: 10.1016/j.bmcl.2005.10.054. Epub 2005 Nov 10. Bioorg Med Chem Lett. 2006. PMID: 16289820 Free PMC article.

3

Stereoselective synthesis of MLN4924, an inhibitor of NEDD8-activating enzyme.

Lee HW, Nam SK, Choi WJ, Kim HO, Jeong LS. Lee HW, et al. Among authors: jeong ls. J Org Chem. 2011 May 6;76(9):3557-61. doi: 10.1021/jo2001897. Epub 2011 Mar 21. J Org Chem. 2011. PMID: 21417215

4

Fluorocyclopentenyl-cytosine with broad spectrum and potent antitumor activity.

Choi WJ, Chung HJ, Chandra G, Alexander V, Zhao LX, Lee HW, Nayak A, Majik MS, Kim HO, Kim JH, Lee YB, Ahn CH, Lee SK, Jeong LS. Choi WJ, et al. Among authors: jeong ls. J Med Chem. 2012 May 10;55(9):4521-5. doi: 10.1021/jm3004009. Epub 2012 May 1. J Med Chem. 2012. PMID: 22524616

5

Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.

Chandra G, Alexander V, Lee HW, Jeong LS. Chandra G, et al. Among authors: jeong ls. Arch Pharm Res. 2012 Mar;35(4):639-45. doi: 10.1007/s12272-012-0407-1. Epub 2012 May 3. Arch Pharm Res. 2012. PMID: 22553056

6

Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.

Luo Z, Pan Y, Jeong LS, Liu J, Jia L. Luo Z, et al. Among authors: jeong ls. Autophagy. 2012 Nov;8(11):1677-9. doi: 10.4161/auto.21484. Epub 2012 Aug 9. Autophagy. 2012. PMID: 22874562 Free PMC article.

7

c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor.

Zuo W, Huang F, Chiang YJ, Li M, Du J, Ding Y, Zhang T, Lee HW, Jeong LS, Chen Y, Deng H, Feng XH, Luo S, Gao C, Chen YG. Zuo W, et al. Among authors: jeong ls. Mol Cell. 2013 Feb 7;49(3):499-510. doi: 10.1016/j.molcel.2012.12.002. Epub 2013 Jan 1. Mol Cell. 2013. PMID: 23290524 Free article.

8

Neddylation pathway regulates the proliferation and survival of macrophages.

Li L, Liu B, Dong T, Lee HW, Yu J, Zheng Y, Gao H, Zhang Y, Chu Y, Liu G, Niu W, Zheng S, Jeong LS, Jia L. Li L, et al. Among authors: jeong ls. Biochem Biophys Res Commun. 2013 Mar 15;432(3):494-8. doi: 10.1016/j.bbrc.2013.02.028. Epub 2013 Feb 14. Biochem Biophys Res Commun. 2013. PMID: 23416079

9

Suppression of tumor angiogenesis by targeting the protein neddylation pathway.

Yao WT, Wu JF, Yu GY, Wang R, Wang K, Li LH, Chen P, Jiang YN, Cheng H, Lee HW, Yu J, Qi H, Yu XJ, Wang P, Chu YW, Yang M, Hua ZC, Ying HQ, Hoffman RM, Jeong LS, Jia LJ. Yao WT, et al. Among authors: jeong ls. Cell Death Dis. 2014 Feb 13;5(2):e1059. doi: 10.1038/cddis.2014.21. Cell Death Dis. 2014. PMID: 24525735 Free PMC article.

10

Overactivated neddylation pathway as a therapeutic target in lung cancer.

Li L, Wang M, Yu G, Chen P, Li H, Wei D, Zhu J, Xie L, Jia H, Shi J, Li C, Yao W, Wang Y, Gao Q, Jeong LS, Lee HW, Yu J, Hu F, Mei J, Wang P, Chu Y, Qi H, Yang M, Dong Z, Sun Y, Hoffman RM, Jia L. Li L, et al. Among authors: jeong ls. J Natl Cancer Inst. 2014 May 22;106(6):dju083. doi: 10.1093/jnci/dju083. Print 2014 Jun. J Natl Cancer Inst. 2014. PMID: 24853380

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