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RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival.
Jia L, Sun Y. Jia L, et al. Among authors: sun y. Cell Div. 2009 Aug 6;4:16. doi: 10.1186/1747-1028-4-16. Cell Div. 2009. PMID: 19660140 Free PMC article.
Differential outcomes between normal (growth arrest) and cancer cells (cell death) upon RBX1 disruption/silencing suggest RBX1 as a valid anticancer target.Comments on:Tan M, Davis SW, Saunders TL, Zhu Y, Sun Y. RBX1/ROC1 disruption results in early embryonic …
Differential outcomes between normal (growth arrest) and cancer cells (cell death) upon RBX1 disruption/silencing suggest RBX1 as a valid an …
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