Ealick SE - Search Results

1

Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.

Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP. Lai RY, et al. Among authors: ealick se. J Am Chem Soc. 2012 Jun 6;134(22):9157-9. doi: 10.1021/ja302474a. Epub 2012 May 24. J Am Chem Soc. 2012. PMID: 22568620 Free PMC article.

2

Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis.

Chatterjee A, Jurgenson CT, Schroeder FC, Ealick SE, Begley TP. Chatterjee A, et al. Among authors: ealick se. J Am Chem Soc. 2006 Jun 7;128(22):7158-9. doi: 10.1021/ja061413o. J Am Chem Soc. 2006. PMID: 16734458 Free PMC article.

3

Thiamin phosphate synthase: the rate of pyrimidine carbocation formation.

Hanes JW, Ealick SE, Begley TP. Hanes JW, et al. Among authors: ealick se. J Am Chem Soc. 2007 Apr 25;129(16):4860-1. doi: 10.1021/ja0679634. Epub 2007 Mar 28. J Am Chem Soc. 2007. PMID: 17388590 Free PMC article. No abstract available.

4

Biosynthesis of the thiamin-thiazole in eukaryotes: identification of a thiazole tautomer intermediate.

Chatterjee A, Schroeder FC, Jurgenson CT, Ealick SE, Begley TP. Chatterjee A, et al. Among authors: ealick se. J Am Chem Soc. 2008 Aug 27;130(34):11394-8. doi: 10.1021/ja802140a. Epub 2008 Jul 25. J Am Chem Soc. 2008. PMID: 18652458 Free PMC article.

5

Domain organization in Candida glabrata THI6, a bifunctional enzyme required for thiamin biosynthesis in eukaryotes.

Paul D, Chatterjee A, Begley TP, Ealick SE. Paul D, et al. Among authors: ealick se. Biochemistry. 2010 Nov 16;49(45):9922-34. doi: 10.1021/bi101008u. Epub 2010 Oct 22. Biochemistry. 2010. PMID: 20968298 Free PMC article.

6

A missing enzyme in thiamin thiazole biosynthesis: identification of TenI as a thiazole tautomerase.

Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP. Hazra AB, et al. Among authors: ealick se. J Am Chem Soc. 2011 Jun 22;133(24):9311-9. doi: 10.1021/ja1110514. Epub 2011 May 26. J Am Chem Soc. 2011. PMID: 21534620 Free PMC article.

7

Identification of the product of toxoflavin lyase: degradation via a Baeyer-Villiger oxidation.

Philmus B, Abdelwahed S, Williams HJ, Fenwick MK, Ealick SE, Begley TP. Philmus B, et al. Among authors: ealick se. J Am Chem Soc. 2012 Mar 21;134(11):5326-30. doi: 10.1021/ja211759n. Epub 2012 Mar 9. J Am Chem Soc. 2012. PMID: 22304755 Free PMC article.

8

Thiamin biosynthesis: still yielding fascinating biological chemistry.

Begley TP, Ealick SE, McLafferty FW. Begley TP, et al. Among authors: ealick se. Biochem Soc Trans. 2012 Jun 1;40(3):555-60. doi: 10.1042/BST20120084. Biochem Soc Trans. 2012. PMID: 22616866 Free PMC article. Review.

9

Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.

Fenwick MK, Mehta AP, Zhang Y, Abdelwahed SH, Begley TP, Ealick SE. Fenwick MK, et al. Among authors: ealick se. Nat Commun. 2015 Mar 27;6:6480. doi: 10.1038/ncomms7480. Nat Commun. 2015. PMID: 25813242 Free PMC article.

10

Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.

Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP. Mehta AP, et al. Among authors: ealick se. J Am Chem Soc. 2015 Aug 26;137(33):10444-7. doi: 10.1021/jacs.5b03576. Epub 2015 Aug 13. J Am Chem Soc. 2015. PMID: 26237670 Free PMC article.

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