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The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.
Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A. Smiljanovic B, et al. Among authors: haupl t. J Mol Med (Berl). 2012 Nov;90(11):1295-309. doi: 10.1007/s00109-012-0907-y. Epub 2012 May 19. J Mol Med (Berl). 2012. PMID: 22610275
Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic options.
Strauß R, Rose T, Flint SM, Klotsche J, Häupl T, Peck-Radosavljevic M, Yoshida T, Kyogoku C, Flechsig A, Becker AM, Dao KH, Radbruch A, Burmester GR, Lyons PA, Davis LS, Hiepe F, Grützkau A, Biesen R. Strauß R, et al. Among authors: haupl t. J Mol Med (Berl). 2017 Jul;95(7):753-765. doi: 10.1007/s00109-017-1515-7. Epub 2017 Mar 29. J Mol Med (Berl). 2017. PMID: 28357476
Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus.
Biesen R, Demir C, Barkhudarova F, Grün JR, Steinbrich-Zöllner M, Backhaus M, Häupl T, Rudwaleit M, Riemekasten G, Radbruch A, Hiepe F, Burmester GR, Grützkau A. Biesen R, et al. Among authors: haupl t. Arthritis Rheum. 2008 Apr;58(4):1136-45. doi: 10.1002/art.23404. Arthritis Rheum. 2008. PMID: 18383365 Free article.
Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint.
Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Schulte-Wrede U, Sörensen T, Kyogoku C, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, Grützkau A, Maslinski W, Häupl T. Smiljanovic B, et al. Among authors: haupl t. Ann Rheum Dis. 2018 Feb;77(2):300-308. doi: 10.1136/annrheumdis-2017-211649. Epub 2017 Nov 30. Ann Rheum Dis. 2018. PMID: 29191820 Free PMC article.
An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus.
Schulte-Wrede U, Sörensen T, Grün JR, Häupl T, Hirseland H, Steinbrich-Zöllner M, Wu P, Radbruch A, Poddubnyy D, Sieper J, Syrbe U, Grützkau A. Schulte-Wrede U, et al. Among authors: haupl t. Arthritis Res Ther. 2018 Aug 29;20(1):191. doi: 10.1186/s13075-018-1692-y. Arthritis Res Ther. 2018. PMID: 30157966 Free PMC article.
Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation.
Smiljanovic B, Grützkau A, Sörensen T, Grün JR, Vogl T, Bonin M, Schendel P, Stuhlmüller B, Claussnitzer A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Radbruch A, Burmester GR, Häupl T. Smiljanovic B, et al. Among authors: haupl t. Sci Rep. 2020 May 13;10(1):7907. doi: 10.1038/s41598-020-64431-4. Sci Rep. 2020. PMID: 32404914 Free PMC article.
Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint.
Karow F, Smiljanovic B, Grün JR, Poddubnyy D, Proft F, Talpin A, Hue C, Boland A, Deleuze JF, Garchon HJ, Ergenç I, De Craemer AS, Erben U, Häupl T, Elewaut D, Breban M, Grützkau A, Syrbe U. Karow F, et al. Among authors: haupl t. Arthritis Res Ther. 2021 Sep 24;23(1):246. doi: 10.1186/s13075-021-02623-7. Arthritis Res Ther. 2021. PMID: 34560894 Free PMC article.
147 results