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Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.
Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Capparelli C, et al. Among authors: guido c. Cell Cycle. 2012 Jun 15;11(12):2285-302. doi: 10.4161/cc.20718. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22684298 Free PMC article.
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.
Guido C, Whitaker-Menezes D, Capparelli C, Balliet R, Lin Z, Pestell RG, Howell A, Aquila S, Andò S, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Guido C, et al. Cell Cycle. 2012 Aug 15;11(16):3019-35. doi: 10.4161/cc.21384. Epub 2012 Aug 9. Cell Cycle. 2012. PMID: 22874531 Free PMC article.
Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.
Balliet RM, Capparelli C, Guido C, Pestell TG, Martinez-Outschoorn UE, Lin Z, Whitaker-Menezes D, Chiavarina B, Pestell RG, Howell A, Sotgia F, Lisanti MP. Balliet RM, et al. Among authors: guido c. Cell Cycle. 2011 Dec 1;10(23):4065-73. doi: 10.4161/cc.10.23.18254. Epub 2011 Dec 1. Cell Cycle. 2011. PMID: 22129993 Free PMC article.
CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.
Capparelli C, Whitaker-Menezes D, Guido C, Balliet R, Pestell TG, Howell A, Sneddon S, Pestell RG, Martinez-Outschoorn U, Lisanti MP, Sotgia F. Capparelli C, et al. Among authors: guido c. Cell Cycle. 2012 Jun 15;11(12):2272-84. doi: 10.4161/cc.20717. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22684333 Free PMC article.
Estrogen receptor beta (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene.
Guido C, Panza S, Santoro M, Avena P, Panno ML, Perrotta I, Giordano F, Casaburi I, Catalano S, De Amicis F, Sotgia F, Lisanti MP, Andò S, Aquila S. Guido C, et al. Cell Cycle. 2012 Aug 1;11(15):2911-21. doi: 10.4161/cc.21336. Epub 2012 Aug 1. Cell Cycle. 2012. PMID: 22810004
Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer cells.
De Amicis F, Guido C, Santoro M, Giordano F, Donà A, Rizza P, Pellegrino M, Perrotta I, Bonofiglio D, Sisci D, Panno ML, Tramontano D, Aquila S, Andò S. De Amicis F, et al. Among authors: guido c. Oncotarget. 2016 Sep 6;7(36):57955-57969. doi: 10.18632/oncotarget.10799. Oncotarget. 2016. PMID: 27462784 Free PMC article.
130 results