Kinnula VL - Search Results

1

Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease.

Rahman I, Kinnula VL. Rahman I, et al. Among authors: kinnula vl. Expert Rev Clin Pharmacol. 2012 May;5(3):293-309. doi: 10.1586/ecp.12.16. Expert Rev Clin Pharmacol. 2012. PMID: 22697592 Free PMC article. Review.

2

SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.

Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. Rajendrasozhan S, et al. Among authors: kinnula vl. Am J Respir Crit Care Med. 2008 Apr 15;177(8):861-70. doi: 10.1164/rccm.200708-1269OC. Epub 2008 Jan 3. Am J Respir Crit Care Med. 2008. PMID: 18174544 Free PMC article.

3

FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease.

Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I. Hwang JW, et al. Among authors: kinnula vl. J Immunol. 2011 Jul 15;187(2):987-98. doi: 10.4049/jimmunol.1001861. Epub 2011 Jun 20. J Immunol. 2011. PMID: 21690325 Free PMC article.

4

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease.

Rahman I, Kinnula VL, Gorbunova V, Yao H. Rahman I, et al. Among authors: kinnula vl. Prev Med. 2012 May;54 Suppl(Suppl):S20-8. doi: 10.1016/j.ypmed.2011.11.014. Epub 2011 Dec 8. Prev Med. 2012. PMID: 22178470 Free PMC article. Review.

5

SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.

Yao H, Hwang JW, Sundar IK, Friedman AE, McBurney MW, Guarente L, Gu W, Kinnula VL, Rahman I. Yao H, et al. Among authors: kinnula vl. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L615-24. doi: 10.1152/ajplung.00249.2012. Epub 2013 Sep 13. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 24039251 Free PMC article.

6

Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: current and future perspectives.

Louhelainen N, Myllärniemi M, Rahman I, Kinnula VL. Louhelainen N, et al. Among authors: kinnula vl. Int J Chron Obstruct Pulmon Dis. 2008;3(4):585-603. doi: 10.2147/copd.s3671. Int J Chron Obstruct Pulmon Dis. 2008. PMID: 19281076 Free PMC article. Review.

7

Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM.

Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I. Yao H, et al. Among authors: kinnula vl. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15571-6. doi: 10.1073/pnas.1007625107. Epub 2010 Aug 16. Proc Natl Acad Sci U S A. 2010. PMID: 20713693 Free PMC article.

8

Peroxiredoxin 6 differentially regulates acute and chronic cigarette smoke–mediated lung inflammatory response and injury.

Sundar IK, Chung S, Hwang JW, Arunachalam G, Cook S, Yao H, Mazur W, Kinnula VL, Fisher AB, Rahman I. Sundar IK, et al. Among authors: kinnula vl. Exp Lung Res. 2010 Oct;36(8):451-62. doi: 10.3109/01902141003754128. Exp Lung Res. 2010. PMID: 20939758 Free PMC article.

9

NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.

Chung S, Sundar IK, Hwang JW, Yull FE, Blackwell TS, Kinnula VL, Bulger M, Yao H, Rahman I. Chung S, et al. Among authors: kinnula vl. PLoS One. 2011;6(8):e23488. doi: 10.1371/journal.pone.0023488. Epub 2011 Aug 24. PLoS One. 2011. PMID: 21887257 Free PMC article.

10

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.

Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, Rönty M, Kinnula VL, Rahman I. Yao H, et al. Among authors: kinnula vl. J Clin Invest. 2012 Jun;122(6):2032-45. doi: 10.1172/JCI60132. Epub 2012 May 1. J Clin Invest. 2012. PMID: 22546858 Free PMC article.

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