Siminovitch KA - Search Results

1

Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance.

Xu E, Charbonneau A, Rolland Y, Bellmann K, Pao L, Siminovitch KA, Neel BG, Beauchemin N, Marette A. Xu E, et al. Among authors: siminovitch ka. Diabetes. 2012 Aug;61(8):1949-58. doi: 10.2337/db11-1502. Epub 2012 Jun 14. Diabetes. 2012. PMID: 22698917 Free PMC article.

2

Hepatocyte-specific Ptpn6 deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: potential role of PPARγ.

Xu E, Forest MP, Schwab M, Avramoglu RK, St-Amand E, Caron AZ, Bellmann K, Shum M, Voisin G, Paquet M, Montoudis A, Lévy E, Siminovitch KA, Neel BG, Beauchemin N, Marette A. Xu E, et al. Among authors: siminovitch ka. Hepatology. 2014 May;59(5):1803-15. doi: 10.1002/hep.26957. Epub 2014 Apr 1. Hepatology. 2014. PMID: 24327268

3

The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis.

Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournès B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A. Dubois MJ, et al. Among authors: siminovitch ka. Nat Med. 2006 May;12(5):549-56. doi: 10.1038/nm1397. Epub 2006 Apr 16. Nat Med. 2006. PMID: 16617349

4

Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization.

Fiset A, Xu E, Bergeron S, Marette A, Pelletier G, Siminovitch KA, Olivier M, Beauchemin N, Faure RL. Fiset A, et al. Among authors: siminovitch ka. Cell Signal. 2011 May;23(5):911-9. doi: 10.1016/j.cellsig.2011.01.019. Epub 2011 Jan 22. Cell Signal. 2011. PMID: 21262353

5

Nonreceptor protein-tyrosine phosphatases in immune cell signaling.

Pao LI, Badour K, Siminovitch KA, Neel BG. Pao LI, et al. Among authors: siminovitch ka. Annu Rev Immunol. 2007;25:473-523. doi: 10.1146/annurev.immunol.23.021704.115647. Annu Rev Immunol. 2007. PMID: 17291189 Review.

6

Regulation of the Leishmania-induced innate inflammatory response by the protein tyrosine phosphatase SHP-1.

Forget G, Matte C, Siminovitch KA, Rivest S, Pouliot P, Olivier M. Forget G, et al. Among authors: siminovitch ka. Eur J Immunol. 2005 Jun;35(6):1906-17. doi: 10.1002/eji.200526037. Eur J Immunol. 2005. PMID: 15902687 Free article.

7

The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness.

Zhang J, Zahir N, Jiang Q, Miliotis H, Heyraud S, Meng X, Dong B, Xie G, Qiu F, Hao Z, McCulloch CA, Keystone EC, Peterson AC, Siminovitch KA. Zhang J, et al. Among authors: siminovitch ka. Nat Genet. 2011 Aug 14;43(9):902-7. doi: 10.1038/ng.904. Nat Genet. 2011. PMID: 21841778

8

Involvement of the Wiskott-Aldrich syndrome protein and other actin regulatory adaptors in T cell activation.

Badour K, Zhang J, Siminovitch KA. Badour K, et al. Among authors: siminovitch ka. Semin Immunol. 2004 Dec;16(6):395-407. doi: 10.1016/j.smim.2004.08.019. Semin Immunol. 2004. PMID: 15541654 Review.

9

The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation.

Badour K, Zhang J, Siminovitch KA. Badour K, et al. Among authors: siminovitch ka. Immunol Rev. 2003 Apr;192:98-112. doi: 10.1034/j.1600-065x.2003.00031.x. Immunol Rev. 2003. PMID: 12670398 Review.

10

Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation.

Badour K, Zhang J, Shi F, Leng Y, Collins M, Siminovitch KA. Badour K, et al. Among authors: siminovitch ka. J Exp Med. 2004 Jan 5;199(1):99-112. doi: 10.1084/jem.20030976. J Exp Med. 2004. PMID: 14707117 Free PMC article.

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