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Antagonism of sigma-1 receptors blocks compulsive-like eating.
Cottone P, Wang X, Park JW, Valenza M, Blasio A, Kwak J, Iyer MR, Steardo L, Rice KC, Hayashi T, Sabino V. Cottone P, et al. Among authors: steardo l. Neuropsychopharmacology. 2012 Nov;37(12):2593-604. doi: 10.1038/npp.2012.89. Epub 2012 Jun 20. Neuropsychopharmacology. 2012. PMID: 22713906 Free PMC article.
Long-term effects on cortical glutamate release induced by prenatal exposure to the cannabinoid receptor agonist (R)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinyl-methyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone: an in vivo microdialysis study in the awake rat.
Antonelli T, Tanganelli S, Tomasini MC, Finetti S, Trabace L, Steardo L, Sabino V, Carratu MR, Cuomo V, Ferraro L. Antonelli T, et al. Among authors: steardo l. Neuroscience. 2004;124(2):367-75. doi: 10.1016/j.neuroscience.2003.10.034. Neuroscience. 2004. PMID: 14980386
Sigma-1 receptor knockout mice display a depressive-like phenotype.
Sabino V, Cottone P, Parylak SL, Steardo L, Zorrilla EP. Sabino V, et al. Among authors: steardo l. Behav Brain Res. 2009 Mar 17;198(2):472-6. doi: 10.1016/j.bbr.2008.11.036. Epub 2008 Nov 30. Behav Brain Res. 2009. PMID: 19100292 Free PMC article.
249 results