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RhoC and ROCKs regulate cancer cell interactions with endothelial cells.
Reymond N, Im JH, Garg R, Cox S, Soyer M, Riou P, Colomba A, Muschel RJ, Ridley AJ. Reymond N, et al. Among authors: colomba a. Mol Oncol. 2015 Jun;9(6):1043-55. doi: 10.1016/j.molonc.2015.01.004. Epub 2015 Jan 22. Mol Oncol. 2015. PMID: 25677806 Free PMC article.
RhoBTB1 interacts with ROCKs and inhibits invasion.
Haga RB, Garg R, Collu F, Borda D'Agua B, Menéndez ST, Colomba A, Fraternali F, Ridley AJ. Haga RB, et al. Among authors: colomba a. Biochem J. 2019 Sep 13;476(17):2499-2514. doi: 10.1042/BCJ20190203. Biochem J. 2019. PMID: 31431478 Free PMC article.
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.
Claus J, Patel G, Autore F, Colomba A, Weitsman G, Soliman TN, Roberts S, Zanetti-Domingues LC, Hirsch M, Collu F, George R, Ortiz-Zapater E, Barber PR, Vojnovic B, Yarden Y, Martin-Fernandez ML, Cameron A, Fraternali F, Ng T, Parker PJ. Claus J, et al. Among authors: colomba a. Elife. 2018 May 1;7:e32271. doi: 10.7554/eLife.32271. Elife. 2018. PMID: 29712619 Free PMC article.
A small molecule inhibitor of HER3: a proof-of-concept study.
Colomba A, Fitzek M, George R, Weitsman G, Roberts S, Zanetti-Domingues L, Hirsch M, Rolfe DJ, Mehmood S, Madin A, Claus J, Kjaer S, Snijders AP, Ng T, Martin-Fernandez M, Smith DM, Parker PJ. Colomba A, et al. Biochem J. 2020 Sep 18;477(17):3329-3347. doi: 10.1042/BCJ20200496. Biochem J. 2020. PMID: 32815546 Free PMC article.
33 results