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Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function.
Lee LF, Logronio K, Tu GH, Zhai W, Ni I, Mei L, Dilley J, Yu J, Rajpal A, Brown C, Appah C, Chin SM, Han B, Affolter T, Lin JC. Lee LF, et al. Among authors: zhai w. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12674-9. doi: 10.1073/pnas.1203795109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733769 Free PMC article.
Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.
Glanville J, Zhai W, Berka J, Telman D, Huerta G, Mehta GR, Ni I, Mei L, Sundar PD, Day GM, Cox D, Rajpal A, Pons J. Glanville J, et al. Among authors: zhai w. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20216-21. doi: 10.1073/pnas.0909775106. Epub 2009 Oct 29. Proc Natl Acad Sci U S A. 2009. PMID: 19875695 Free PMC article.
Synthetic antibodies designed on natural sequence landscapes.
Zhai W, Glanville J, Fuhrmann M, Mei L, Ni I, Sundar PD, Van Blarcom T, Abdiche Y, Lindquist K, Strohner R, Telman D, Cappuccilli G, Finlay WJ, Van den Brulle J, Cox DR, Pons J, Rajpal A. Zhai W, et al. J Mol Biol. 2011 Sep 9;412(1):55-71. doi: 10.1016/j.jmb.2011.07.018. Epub 2011 Jul 23. J Mol Biol. 2011. PMID: 21787786
Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.
Van Blarcom T, Lindquist K, Melton Z, Cheung WL, Wagstrom C, McDonough D, Valle Oseguera C, Ding S, Rossi A, Potluri S, Sundar P, Pitts S, Sirota M, Galindo Casas M, Yan Y, Jones J, Roe-Zurz Z, Srivatsa Srinivasan S, Zhai W, Pons J, Rajpal A, Chaparro-Riggers J. Van Blarcom T, et al. Among authors: zhai w. MAbs. 2018 Feb/Mar;10(2):256-268. doi: 10.1080/19420862.2017.1406570. Epub 2017 Dec 14. MAbs. 2018. PMID: 29227213 Free PMC article.
Epitope Mapping Using Yeast Display and Next Generation Sequencing.
Van Blarcom T, Rossi A, Foletti D, Sundar P, Pitts S, Melton Z, Telman D, Zhao L, Cheung WL, Berka J, Zhai W, Strop P, Pons J, Rajpal A, Chaparro-Riggers J. Van Blarcom T, et al. Among authors: zhai w. Methods Mol Biol. 2018;1785:89-118. doi: 10.1007/978-1-4939-7841-0_7. Methods Mol Biol. 2018. PMID: 29714014
Precise and efficient antibody epitope determination through library design, yeast display and next-generation sequencing.
Van Blarcom T, Rossi A, Foletti D, Sundar P, Pitts S, Bee C, Melton Witt J, Melton Z, Hasa-Moreno A, Shaughnessy L, Telman D, Zhao L, Cheung WL, Berka J, Zhai W, Strop P, Chaparro-Riggers J, Shelton DL, Pons J, Rajpal A. Van Blarcom T, et al. Among authors: zhai w. J Mol Biol. 2015 Mar 27;427(6 Pt B):1513-1534. doi: 10.1016/j.jmb.2014.09.020. Epub 2014 Oct 2. J Mol Biol. 2015. PMID: 25284753
1,544 results