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C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms.
Heydenreich N, Nolte MW, Göb E, Langhauser F, Hofmeister M, Kraft P, Albert-Weissenberger C, Brede M, Varallyay C, Göbel K, Meuth SG, Nieswandt B, Dickneite G, Stoll G, Kleinschnitz C. Heydenreich N, et al. Among authors: nolte mw. Stroke. 2012 Sep;43(9):2457-67. doi: 10.1161/STROKEAHA.112.660340. Epub 2012 Jun 28. Stroke. 2012. PMID: 22744646
C1-Inhibitor protects from focal brain trauma in a cortical cryolesion mice model by reducing thrombo-inflammation.
Albert-Weissenberger C, Mencl S, Schuhmann MK, Salur I, Göb E, Langhauser F, Hopp S, Hennig N, Meuth SG, Nolte MW, Sirén AL, Kleinschnitz C. Albert-Weissenberger C, et al. Among authors: nolte mw. Front Cell Neurosci. 2014 Sep 9;8:269. doi: 10.3389/fncel.2014.00269. eCollection 2014. Front Cell Neurosci. 2014. PMID: 25249935 Free PMC article.
Targeting coagulation factor XII as a novel therapeutic option in brain trauma.
Hopp S, Albert-Weissenberger C, Mencl S, Bieber M, Schuhmann MK, Stetter C, Nieswandt B, Schmidt PM, Monoranu CM, Alafuzoff I, Marklund N, Nolte MW, Sirén AL, Kleinschnitz C. Hopp S, et al. Among authors: nolte mw. Ann Neurol. 2016 Jun;79(6):970-82. doi: 10.1002/ana.24655. Epub 2016 Apr 28. Ann Neurol. 2016. PMID: 27043916 Free PMC article.
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Göbel K, Pankratz S, Asaridou CM, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG. Göbel K, et al. Among authors: nolte mw. Nat Commun. 2016 May 18;7:11626. doi: 10.1038/ncomms11626. Nat Commun. 2016. PMID: 27188843 Free PMC article.
43 results