Kuwahara M - Search Results

1

The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation.

Kuwahara M, Yamashita M, Shinoda K, Tofukuji S, Onodera A, Shinnakasu R, Motohashi S, Hosokawa H, Tumes D, Iwamura C, Lefebvre V, Nakayama T. Kuwahara M, et al. Nat Immunol. 2012 Jul 1;13(8):778-86. doi: 10.1038/ni.2362. Nat Immunol. 2012. PMID: 22751141 Free PMC article.

2

Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene.

Yamashita M, Kuwahara M, Suzuki A, Hirahara K, Shinnaksu R, Hosokawa H, Hasegawa A, Motohashi S, Iwama A, Nakayama T. Yamashita M, et al. Among authors: kuwahara m. J Exp Med. 2008 May 12;205(5):1109-20. doi: 10.1084/jem.20072000. Epub 2008 Apr 14. J Exp Med. 2008. PMID: 18411339 Free PMC article.

3

Gfi1-mediated stabilization of GATA3 protein is required for Th2 cell differentiation.

Shinnakasu R, Yamashita M, Kuwahara M, Hosokawa H, Hasegawa A, Motohashi S, Nakayama T. Shinnakasu R, et al. Among authors: kuwahara m. J Biol Chem. 2008 Oct 17;283(42):28216-25. doi: 10.1074/jbc.M804174200. Epub 2008 Aug 13. J Biol Chem. 2008. PMID: 18701459 Free PMC article.

4

STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.

Onodera A, Yamashita M, Endo Y, Kuwahara M, Tofukuji S, Hosokawa H, Kanai A, Suzuki Y, Nakayama T. Onodera A, et al. Among authors: kuwahara m. J Exp Med. 2010 Oct 25;207(11):2493-506. doi: 10.1084/jem.20100760. Epub 2010 Oct 18. J Exp Med. 2010. PMID: 20956546 Free PMC article.

5

Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3.

Endo Y, Iwamura C, Kuwahara M, Suzuki A, Sugaya K, Tumes DJ, Tokoyoda K, Hosokawa H, Yamashita M, Nakayama T. Endo Y, et al. Among authors: kuwahara m. Immunity. 2011 Nov 23;35(5):733-45. doi: 10.1016/j.immuni.2011.08.017. Immunity. 2011. PMID: 22118525 Free article.

6

Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGF-β.

Tofukuji S, Kuwahara M, Suzuki J, Ohara O, Nakayama T, Yamashita M. Tofukuji S, et al. Among authors: kuwahara m. J Immunol. 2012 May 15;188(10):4846-57. doi: 10.4049/jimmunol.1103799. Epub 2012 Apr 13. J Immunol. 2012. PMID: 22504655

7

A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus.

Suzuki J, Kuwahara M, Tofukuji S, Imamura M, Kato F, Nakayama T, Ohara O, Yamashita M. Suzuki J, et al. Among authors: kuwahara m. PLoS One. 2013 Apr 16;8(4):e61785. doi: 10.1371/journal.pone.0061785. Print 2013. PLoS One. 2013. PMID: 23613936 Free PMC article.

8

The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.

Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T, Yamashita M. Kuwahara M, et al. Nat Commun. 2014 Apr 2;5:3555. doi: 10.1038/ncomms4555. Nat Commun. 2014. PMID: 24694524 Free PMC article.

9

A novel function of interferon regulatory factor-1: inhibition of Th2 cells by down-regulating the Il4 gene during Listeria infection.

Maruyama S, Kanoh M, Matsumoto A, Kuwahara M, Yamashita M, Asano Y. Maruyama S, et al. Among authors: kuwahara m. Int Immunol. 2015 Mar;27(3):143-52. doi: 10.1093/intimm/dxu092. Epub 2014 Oct 3. Int Immunol. 2015. PMID: 25280793

10

Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.

Suzuki J, Maruyama S, Tamauchi H, Kuwahara M, Horiuchi M, Mizuki M, Ochi M, Sawasaki T, Zhu J, Yasukawa M, Yamashita M. Suzuki J, et al. Among authors: kuwahara m. Immunology. 2016 Apr;147(4):476-87. doi: 10.1111/imm.12580. Epub 2016 Feb 9. Immunology. 2016. PMID: 26749286 Free PMC article.

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