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Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.
Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D. Dentice M, et al. Among authors: luongo c. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14466-71. doi: 10.1073/pnas.0706754104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720805 Free PMC article.
The Thyroid Hormone Inactivator Enzyme, Type 3 Deiodinase, Is Essential for Coordination of Keratinocyte Growth and Differentiation.
Mancino G, Sibilio A, Luongo C, Di Cicco E, Miro C, Cicatiello AG, Nappi A, Sagliocchi S, Ambrosio R, De Stefano MA, Di Girolamo D, Porcelli T, Murolo M, Saracino F, Perruolo G, Formisano P, Stornaiuolo M, Dentice M. Mancino G, et al. Among authors: luongo c. Thyroid. 2020 Jul;30(7):1066-1078. doi: 10.1089/thy.2019.0557. Epub 2020 Apr 29. Thyroid. 2020. PMID: 32111151
Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.
Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D. Dentice M, et al. Among authors: luongo c. Cell Metab. 2014 Dec 2;20(6):1038-48. doi: 10.1016/j.cmet.2014.10.009. Epub 2014 Nov 13. Cell Metab. 2014. PMID: 25456740 Free PMC article.
180 results