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Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.
Oswald S, Haenisch S, Fricke C, Sudhop T, Remmler C, Giessmann T, Jedlitschky G, Adam U, Dazert E, Warzok R, Wacke W, Cascorbi I, Kroemer HK, Weitschies W, von Bergmann K, Siegmund W. Oswald S, et al. Among authors: siegmund w. Clin Pharmacol Ther. 2006 Mar;79(3):206-17. doi: 10.1016/j.clpt.2005.11.004. Epub 2006 Feb 7. Clin Pharmacol Ther. 2006. PMID: 16513445
Transporter-mediated uptake into cellular compartments.
Oswald S, Grube M, Siegmund W, Kroemer HK. Oswald S, et al. Among authors: siegmund w. Xenobiotica. 2007 Oct-Nov;37(10-11):1171-95. doi: 10.1080/00498250701570251. Xenobiotica. 2007. PMID: 17968742 Review.
213 results