Clapham KM - Search Results

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Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives.

Clapham KM, Rennison T, Jones G, Craven F, Bardos J, Golding BT, Griffin RJ, Haggerty K, Hardcastle IR, Thommes P, Ting A, Cano C. Clapham KM, et al. Org Biomol Chem. 2012 Sep 7;10(33):6747-57. doi: 10.1039/c2ob26035b. Epub 2012 Jul 19. Org Biomol Chem. 2012. PMID: 22814419

DNA-dependent protein kinase (DNA-PK) inhibitors: structure-activity relationships for O-alkoxyphenylchromen-4-one probes of the ATP-binding domain.

Clapham KM, Bardos J, Finlay MR, Golding BT, Griffen EJ, Griffin RJ, Hardcastle IR, Menear KA, Ting A, Turner P, Young GL, Cano C. Clapham KM, et al. Bioorg Med Chem Lett. 2011 Feb 1;21(3):966-70. doi: 10.1016/j.bmcl.2010.12.047. Epub 2010 Dec 13. Bioorg Med Chem Lett. 2011. PMID: 21216595

Versatile synthesis of functionalised dibenzothiophenes via Suzuki coupling and microwave-assisted ring closure.

Rodriguez-Aristegui S, Clapham KM, Barrett L, Cano C, Desage-El Murr M, Griffin RJ, Hardcastle IR, Payne SL, Rennison T, Richardson C, Golding BT. Rodriguez-Aristegui S, et al. Among authors: clapham km. Org Biomol Chem. 2011 Sep 7;9(17):6066-74. doi: 10.1039/c1ob05282a. Epub 2011 Jul 12. Org Biomol Chem. 2011. PMID: 21748189

Functionalized heteroarylpyridazines and pyridazin-3(2H)-one derivatives via palladium-catalyzed cross-coupling methodology.

Clapham KM, Batsanov AS, Greenwood RD, Bryce MR, Smith AE, Tarbit B. Clapham KM, et al. J Org Chem. 2008 Mar 21;73(6):2176-81. doi: 10.1021/jo702420q. Epub 2008 Feb 23. J Org Chem. 2008. PMID: 18294000

Trifluoromethyl-substituted pyridyl- and pyrazolylboronic acids and esters: synthesis and Suzuki-Miyaura cross-coupling reactions.

Clapham KM, Batsanov AS, Bryce MR, Tarbit B. Clapham KM, et al. Org Biomol Chem. 2009 May 21;7(10):2155-61. doi: 10.1039/b901024f. Epub 2009 Mar 26. Org Biomol Chem. 2009. PMID: 19421454

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