Fagan AM - Search Results

1

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease.

Cruchaga C, Kauwe JS, Nowotny P, Bales K, Pickering EH, Mayo K, Bertelsen S, Hinrichs A; Alzheimer's Disease Neuroimaging Initiative; Fagan AM, Holtzman DM, Morris JC, Goate AM. Cruchaga C, et al. Among authors: fagan am. Hum Mol Genet. 2012 Oct 15;21(20):4558-71. doi: 10.1093/hmg/dds296. Epub 2012 Jul 20. Hum Mol Genet. 2012. PMID: 22821396 Free PMC article.

2

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Neurobiol Dis. 2002 Apr;9(3):305-18. doi: 10.1006/nbdi.2002.0483. Neurobiol Dis. 2002. PMID: 11950276

3

Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein.

Narita M, Holtzman DM, Fagan AM, LaDu MJ, Yu L, Han X, Gross RW, Bu G, Schwartz AL. Narita M, et al. Among authors: fagan am. J Biochem. 2002 Nov;132(5):743-9. doi: 10.1093/oxfordjournals.jbchem.a003282. J Biochem. 2002. PMID: 12417024 Free article.

4

Novel role for apolipoprotein E in the central nervous system. Modulation of sulfatide content.

Han X, Cheng H, Fryer JD, Fagan AM, Holtzman DM. Han X, et al. Among authors: fagan am. J Biol Chem. 2003 Mar 7;278(10):8043-51. doi: 10.1074/jbc.M212340200. Epub 2002 Dec 24. J Biol Chem. 2003. PMID: 12501252 Free article.

5

Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia.

Han X, Fagan AM, Cheng H, Morris JC, Xiong C, Holtzman DM. Han X, et al. Among authors: fagan am. Ann Neurol. 2003 Jul;54(1):115-9. doi: 10.1002/ana.10618. Ann Neurol. 2003. PMID: 12838527

6

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis.

Fagan AM, Christopher E, Taylor JW, Parsadanian M, Spinner M, Watson M, Fryer JD, Wahrle S, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Am J Pathol. 2004 Oct;165(4):1413-22. doi: 10.1016/s0002-9440(10)63399-8. Am J Pathol. 2004. PMID: 15466405 Free PMC article.

7

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-beta.

Morikawa M, Fryer JD, Sullivan PM, Christopher EA, Wahrle SE, DeMattos RB, O'Dell MA, Fagan AM, Lashuel HA, Walz T, Asai K, Holtzman DM. Morikawa M, et al. Among authors: fagan am. Neurobiol Dis. 2005 Jun-Jul;19(1-2):66-76. doi: 10.1016/j.nbd.2004.11.005. Neurobiol Dis. 2005. PMID: 15837562

8

Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid.

Hu Y, Malone JP, Fagan AM, Townsend RR, Holtzman DM. Hu Y, et al. Among authors: fagan am. Mol Cell Proteomics. 2005 Dec;4(12):2000-9. doi: 10.1074/mcp.M500207-MCP200. Epub 2005 Sep 30. Mol Cell Proteomics. 2005. PMID: 16199891 Free article.

9

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.

Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. Among authors: fagan am. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.

10

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

Fagan AM, Mintun MA, Mach RH, Lee SY, Dence CS, Shah AR, LaRossa GN, Spinner ML, Klunk WE, Mathis CA, DeKosky ST, Morris JC, Holtzman DM. Fagan AM, et al. Ann Neurol. 2006 Mar;59(3):512-9. doi: 10.1002/ana.20730. Ann Neurol. 2006. PMID: 16372280

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