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The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans.
Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, Beckham S, Galle A, McLean C, Morganti-Kossmann C, Rosenfeld JV, Madani R, Vassalli JD, Su EJ, Lawrence DA, Medcalf RL. Sashindranath M, et al. Among authors: beckham s. Brain. 2012 Nov;135(Pt 11):3251-64. doi: 10.1093/brain/aws178. Epub 2012 Jul 20. Brain. 2012. PMID: 22822039 Free PMC article.
A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites.
Beckham SA, Piedrafita D, Phillips CI, Samarawickrema N, Law RH, Smooker PM, Quinsey NS, Irving JA, Greenwood D, Verhelst SH, Bogyo M, Turk B, Coetzer TH, Wijeyewickrema LC, Spithill TW, Pike RN. Beckham SA, et al. Int J Biochem Cell Biol. 2009 Jul;41(7):1601-12. doi: 10.1016/j.biocel.2009.02.003. Epub 2009 Feb 20. Int J Biochem Cell Biol. 2009. PMID: 19401154 Free PMC article.
Protease-associated import systems are widespread in Gram-negative bacteria.
Grinter R, Leung PM, Wijeyewickrema LC, Littler D, Beckham S, Pike RN, Walker D, Greening C, Lithgow T. Grinter R, et al. Among authors: beckham s. PLoS Genet. 2019 Oct 15;15(10):e1008435. doi: 10.1371/journal.pgen.1008435. eCollection 2019 Oct. PLoS Genet. 2019. PMID: 31613892 Free PMC article.
Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8.
Sarvestani ST, Tate MD, Moffat JM, Jacobi AM, Behlke MA, Miller AR, Beckham SA, McCoy CE, Chen W, Mintern JD, O'Keeffe M, John M, Williams BR, Gantier MP. Sarvestani ST, et al. J Virol. 2014 Jan;88(2):799-810. doi: 10.1128/JVI.01571-13. Epub 2013 Nov 13. J Virol. 2014. PMID: 24227841 Free PMC article.
Structural mechanisms of inactivation in scabies mite serine protease paralogues.
Fischer K, Langendorf CG, Irving JA, Reynolds S, Willis C, Beckham S, Law RH, Yang S, Bashtannyk-Puhalovich TA, McGowan S, Whisstock JC, Pike RN, Kemp DJ, Buckle AM. Fischer K, et al. Among authors: beckham s. J Mol Biol. 2009 Jul 24;390(4):635-45. doi: 10.1016/j.jmb.2009.04.082. Epub 2009 May 7. J Mol Biol. 2009. PMID: 19427318
113 results