Cuny GD - Search Results

1

Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability.

Choi S, Keys H, Staples RJ, Yuan J, Degterev A, Cuny GD. Choi S, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5685-8. doi: 10.1016/j.bmcl.2012.06.098. Epub 2012 Jul 6. Bioorg Med Chem Lett. 2012. PMID: 22832318 Free PMC article.

2

Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line.

Liu Y, Lashuel HA, Choi S, Xing X, Case A, Ni J, Yeh LA, Cuny GD, Stein RL, Lansbury PT Jr. Liu Y, et al. Among authors: cuny gd. Chem Biol. 2003 Sep;10(9):837-46. doi: 10.1016/j.chembiol.2003.08.010. Chem Biol. 2003. PMID: 14522054

3

Synthesis, receptor binding and functional studies of mesoridazine stereoisomers.

Choi S, Haggart D, Toll L, Cuny GD. Choi S, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4379-82. doi: 10.1016/j.bmcl.2004.06.078. Bioorg Med Chem Lett. 2004. PMID: 15357957

4

Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression.

Yeh LA, Padmanaban D, Ho P, Xing X, Rowley P, Morse LJ, Jensen RV, Cuny GD. Yeh LA, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1193-6. doi: 10.1016/j.bmcl.2004.12.001. Bioorg Med Chem Lett. 2005. PMID: 15686940

5

Structure-activity relationship study of novel tissue transglutaminase inhibitors.

Duval E, Case A, Stein RL, Cuny GD. Duval E, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1885-9. doi: 10.1016/j.bmcl.2005.02.005. Bioorg Med Chem Lett. 2005. PMID: 15780627

6

Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation.

Ahn JS, Radhakrishnan ML, Mapelli M, Choi S, Tidor B, Cuny GD, Musacchio A, Yeh LA, Kosik KS. Ahn JS, et al. Among authors: cuny gd. Chem Biol. 2005 Jul;12(7):811-23. doi: 10.1016/j.chembiol.2005.05.011. Chem Biol. 2005. PMID: 16039528

7

Structure-activity relationship study of novel necroptosis inhibitors.

Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD. Teng X, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5039-44. doi: 10.1016/j.bmcl.2005.07.077. Bioorg Med Chem Lett. 2005. PMID: 16153840

8

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.

Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. Degterev A, et al. Among authors: cuny gd. Nat Chem Biol. 2005 Jul;1(2):112-9. doi: 10.1038/nchembio711. Epub 2005 May 29. Nat Chem Biol. 2005. PMID: 16408008

9

Structure-activity relationship study of tricyclic necroptosis inhibitors.

Jagtap PG, Degterev A, Choi S, Keys H, Yuan J, Cuny GD. Jagtap PG, et al. Among authors: cuny gd. J Med Chem. 2007 Apr 19;50(8):1886-95. doi: 10.1021/jm061016o. Epub 2007 Mar 16. J Med Chem. 2007. PMID: 17361994

10

Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors.

Mermerian AH, Case A, Stein RL, Cuny GD. Mermerian AH, et al. Among authors: cuny gd. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32. doi: 10.1016/j.bmcl.2007.04.027. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17449248

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