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Carbamazepine inhibits angiotensin I-converting enzyme, linking it to the pathogenesis of temporal lobe epilepsy.
Almeida SS, Naffah-Mazzacoratti MG, Guimarães PB, Wasinski F, Pereira FE, Canzian M, Centeno RS, Carrete H, Yacubian EM, Carmona AK, Vieira RF, Nakaie CR, Sabatini RA, Perosa SR, Bacurau RF, Gouveia TL, Gallo G, Würtele M, Cavalheiro EA, Silva JA Jr, Pesquero JB, Araujo RC. Almeida SS, et al. Among authors: canzian m. Transl Psychiatry. 2012 Mar 13;2(3):e93. doi: 10.1038/tp.2012.21. Transl Psychiatry. 2012. PMID: 22832858 Free PMC article.
Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE).
Simões PSR, Visniauskas B, Perosa SR, Yacubian EMT, Centeno R, Canzian M, Lopes-Cendes I, Maurer Morelli CV, Carrete H Jr, Cavalheiro EA, Tufik S, Chagas JR, Naffah Mazzacoratti MDG. Simões PSR, et al. Among authors: canzian m. Epilepsia. 2014 May;55(5):754-762. doi: 10.1111/epi.12606. Epub 2014 Apr 4. Epilepsia. 2014. PMID: 24702695 Free article.
The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis.
Argañaraz GA, Konno AC, Perosa SR, Santiago JF, Boim MA, Vidotti DB, Varella PP, Costa LG, Canzian M, Porcionatto MA, Yacubian EM, Sakamoto AC, Carrete H Jr, Centeno RS, Amado D, Cavalheiro EA, Junior JA, Mazzacoratti Mda G. Argañaraz GA, et al. Among authors: canzian m. Epilepsia. 2008 Aug;49(8):1348-57. doi: 10.1111/j.1528-1167.2008.01581.x. Epub 2008 Mar 21. Epilepsia. 2008. PMID: 18363708 Free article.
Kallikrein 1 is overexpressed by astrocytes in the hippocampus of patients with refractory temporal lobe epilepsy, associated with hippocampal sclerosis.
Simões PS, Perosa SR, Arganãraz GA, Yacubian EM, Carrete H Jr, Centeno RS, Varella PP, Santiago JF, Canzian M, Silva JA Jr, Mortara RA, Amado D, Cavalheiro EA, Mazzacoratti Mda G. Simões PS, et al. Among authors: canzian m. Neurochem Int. 2011 Mar;58(4):477-82. doi: 10.1016/j.neuint.2010.12.021. Epub 2011 Jan 4. Neurochem Int. 2011. PMID: 21211543
Relationship between fluid-attenuated inversion-recovery (FLAIR) signal intensity and inflammatory mediator's levels in the hippocampus of patients with temporal lobe epilepsy and mesial temporal sclerosis.
Varella PP, Santiago JF, Carrete H Jr, Higa EM, Yacubian EM, Centeno RS, Caboclo LO, Castro Neto EF, Canzian M, Amado D, Cavalheiro EA, Naffah-Mazzacoratti Mda G. Varella PP, et al. Among authors: canzian m. Arq Neuropsiquiatr. 2011 Feb;69(1):91-9. doi: 10.1590/s0004-282x2011000100018. Arq Neuropsiquiatr. 2011. PMID: 21359430 Free article.
47 results