Adkins CE - Search Results

1

Exploiting nutrient transporters at the blood-brain barrier to improve brain distribution of small molecules.

Mittapalli RK, Manda VK, Adkins CE, Geldenhuys WJ, Lockman PR. Mittapalli RK, et al. Among authors: adkins ce. Ther Deliv. 2010 Dec;1(6):775-84. doi: 10.4155/tde.10.76. Ther Deliv. 2010. PMID: 22834013 Review.

2

Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.

Lockman PR, Mittapalli RK, Taskar KS, Rudraraju V, Gril B, Bohn KA, Adkins CE, Roberts A, Thorsheim HR, Gaasch JA, Huang S, Palmieri D, Steeg PS, Smith QR. Lockman PR, et al. Among authors: adkins ce. Clin Cancer Res. 2010 Dec 1;16(23):5664-78. doi: 10.1158/1078-0432.CCR-10-1564. Epub 2010 Sep 9. Clin Cancer Res. 2010. PMID: 20829328 Free PMC article.

3

Nicotine and cotinine increases the brain penetration of saquinavir in rat.

Manda VK, Mittapalli RK, Bohn KA, Adkins CE, Lockman PR. Manda VK, et al. Among authors: adkins ce. J Neurochem. 2010 Dec;115(6):1495-507. doi: 10.1111/j.1471-4159.2010.07054.x. Epub 2010 Nov 11. J Neurochem. 2010. PMID: 20950334 Free article.

4

Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood-brain barrier.

Mittapalli RK, Manda VK, Bohn KA, Adkins CE, Lockman PR. Mittapalli RK, et al. Among authors: adkins ce. J Neurosci Methods. 2013 Sep 30;219(1):188-95. doi: 10.1016/j.jneumeth.2013.07.001. Epub 2013 Aug 2. J Neurosci Methods. 2013. PMID: 23916719 Free PMC article.

5

Molecular determinants of blood-brain barrier permeation.

Geldenhuys WJ, Mohammad AS, Adkins CE, Lockman PR. Geldenhuys WJ, et al. Among authors: adkins ce. Ther Deliv. 2015;6(8):961-71. doi: 10.4155/tde.15.32. Epub 2015 Aug 25. Ther Deliv. 2015. PMID: 26305616 Free PMC article. Review.

6

Unsanctifying the sanctuary: challenges and opportunities with brain metastases.

Puhalla S, Elmquist W, Freyer D, Kleinberg L, Adkins C, Lockman P, McGregor J, Muldoon L, Nesbit G, Peereboom D, Smith Q, Walker S, Neuwelt E. Puhalla S, et al. Neuro Oncol. 2015 May;17(5):639-51. doi: 10.1093/neuonc/nov023. Neuro Oncol. 2015. PMID: 25846288 Free PMC article. Review.

7

Paclitaxel-hyaluronic nanoconjugates prolong overall survival in a preclinical brain metastases of breast cancer model.

Mittapalli RK, Liu X, Adkins CE, Nounou MI, Bohn KA, Terrell TB, Qhattal HS, Geldenhuys WJ, Palmieri D, Steeg PS, Smith QR, Lockman PR. Mittapalli RK, et al. Among authors: adkins ce. Mol Cancer Ther. 2013 Nov;12(11):2389-99. doi: 10.1158/1535-7163.MCT-13-0132. Epub 2013 Sep 3. Mol Cancer Ther. 2013. PMID: 24002934 Free PMC article.

8

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model.

Adkins CE, Mittapalli RK, Manda VK, Nounou MI, Mohammad AS, Terrell TB, Bohn KA, Yasemin C, Grothe TR, Lockman JA, Lockman PR. Adkins CE, et al. Front Pharmacol. 2013 Nov 4;4:136. doi: 10.3389/fphar.2013.00136. eCollection 2013. Front Pharmacol. 2013. PMID: 24312053 Free PMC article.

9

A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrier.

Adkins CE, Nounou MI, Mittapalli RK, Terrell-Hall TB, Mohammad AS, Jagannathan R, Lockman PR. Adkins CE, et al. Cancer Prev Res (Phila). 2015 Jan;8(1):68-76. doi: 10.1158/1940-6207.CAPR-14-0225. Epub 2014 Oct 27. Cancer Prev Res (Phila). 2015. PMID: 25348853 Free PMC article.

10

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer.

Adkins CE, Nounou MI, Hye T, Mohammad AS, Terrell-Hall T, Mohan NK, Eldon MA, Hoch U, Lockman PR. Adkins CE, et al. BMC Cancer. 2015 Oct 13;15:685. doi: 10.1186/s12885-015-1672-4. BMC Cancer. 2015. PMID: 26463521 Free PMC article.

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