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Novel antiangiogenic therapies against advanced hepatocellular carcinoma (HCC).
Pazo-Cid RA, Lanzuela M, Esquerdo G, Pérez-Gracia JL, Antón A, Amigo G, Trufero JM, García-Otín AL, Martín-Duque P. Pazo-Cid RA, et al. Among authors: garcia otin al. Clin Transl Oncol. 2012 Aug;14(8):564-74. doi: 10.1007/s12094-012-0842-y. Epub 2012 Jul 18. Clin Transl Oncol. 2012. PMID: 22855137
Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.
Lozano-Gerona J, Oliván-Viguera A, Delgado-Wicke P, Singh V, Brown BM, Tapia-Casellas E, Pueyo E, Valero MS, Garcia-Otín ÁL, Giraldo P, Abarca-Lachen E, Surra JC, Osada J, Hamilton KL, Raychaudhuri SP, Marigil M, Juarranz Á, Wulff H, Miura H, Gilaberte Y, Köhler R. Lozano-Gerona J, et al. Among authors: garcia otin al. PLoS One. 2020 Mar 9;15(3):e0222619. doi: 10.1371/journal.pone.0222619. eCollection 2020. PLoS One. 2020. PMID: 32150577 Free PMC article.
KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility.
Valero MS, Ramón-Gimenez M, Lozano-Gerona J, Delgado-Wicke P, Calmarza P, Oliván-Viguera A, López V, Garcia-Otín ÁL, Valero S, Pueyo E, Hamilton KL, Miura H, Köhler R. Valero MS, et al. Among authors: garcia otin al. Int J Mol Sci. 2019 Mar 8;20(5):1193. doi: 10.3390/ijms20051193. Int J Mol Sci. 2019. PMID: 30857243 Free PMC article.
Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.
Olivan-Viguera A, Garcia-Otin AL, Lozano-Gerona J, Abarca-Lachen E, Garcia-Malinis AJ, Hamilton KL, Gilaberte Y, Pueyo E, Köhler R. Olivan-Viguera A, et al. Among authors: garcia otin al. PLoS One. 2018 Jan 2;13(1):e0190307. doi: 10.1371/journal.pone.0190307. eCollection 2018. PLoS One. 2018. PMID: 29293584 Free PMC article.
Inhibition of Intermediate-Conductance Calcium-Activated K Channel (KCa3.1) and Fibroblast Mitogenesis by α-Linolenic Acid and Alterations of Channel Expression in the Lysosomal Storage Disorders, Fabry Disease, and Niemann Pick C.
Oliván-Viguera A, Lozano-Gerona J, López de Frutos L, Cebolla JJ, Irún P, Abarca-Lachen E, García-Malinis AJ, García-Otín ÁL, Gilaberte Y, Giraldo P, Köhler R. Oliván-Viguera A, et al. Among authors: garcia otin al. Front Physiol. 2017 Jan 31;8:39. doi: 10.3389/fphys.2017.00039. eCollection 2017. Front Physiol. 2017. PMID: 28197106 Free PMC article.
Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.
Oliván-Viguera A, Valero MS, Pinilla E, Amor S, García-Villalón ÁL, Coleman N, Laría C, Calvín-Tienza V, García-Otín ÁL, Fernández-Fernández JM, Murillo MD, Gálvez JA, Díaz-de-Villegas MD, Badorrey R, Simonsen U, Rivera L, Wulff H, Köhler R. Oliván-Viguera A, et al. Among authors: garcia otin al. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92. doi: 10.1111/bcpt.12560. Epub 2016 Feb 29. Basic Clin Pharmacol Toxicol. 2016. PMID: 26821335 Free PMC article.
40 results