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Page 1
N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor.
Vallin KS, Sterky KJ, Nyman E, Bernström J, From R, Linde C, Minidis AB, Nolting A, Närhi K, Santangelo EM, Sehgelmeble FW, Sohn D, Strindlund J, Weigelt D. Vallin KS, et al. Among authors: sehgelmeble fw. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5485-92. doi: 10.1016/j.bmcl.2012.07.032. Epub 2012 Jul 14. Bioorg Med Chem Lett. 2012. PMID: 22868228
Core refinement toward permeable β-secretase (BACE-1) inhibitors with low hERG activity.
Ginman T, Viklund J, Malmström J, Blid J, Emond R, Forsblom R, Johansson A, Kers A, Lake F, Sehgelmeble F, Sterky KJ, Bergh M, Lindgren A, Johansson P, Jeppsson F, Fälting J, Gravenfors Y, Rahm F. Ginman T, et al. J Med Chem. 2013 Jun 13;56(11):4181-205. doi: 10.1021/jm3011349. Epub 2013 May 20. J Med Chem. 2013. PMID: 23126626
Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy.
Swahn BM, Holenz J, Kihlström J, Kolmodin K, Lindström J, Plobeck N, Rotticci D, Sehgelmeble F, Sundström M, Berg Sv, Fälting J, Georgievska B, Gustavsson S, Neelissen J, Ek M, Olsson LL, Berg S. Swahn BM, et al. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1854-9. doi: 10.1016/j.bmcl.2012.01.079. Epub 2012 Jan 28. Bioorg Med Chem Lett. 2012. PMID: 22325942
Chemical syntheses of inulin and levan structures.
Oscarson S, Sehgelmeble FW. Oscarson S, et al. Among authors: sehgelmeble fw. J Org Chem. 2002 Nov 29;67(24):8457-62. doi: 10.1021/jo020341q. J Org Chem. 2002. PMID: 12444625